Antibody engineering by natural selection and by design

Project Information

ENGRAB

Grant agreement ID: 885539

DOI

10.3030/885539

EC signature date 29 October 2020

Start date 1 November 2020

End date 31 October 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 478 125,00

EU contribution

€ 2 478 125,00

Coordinated by

FONDAZIONE ISTITUTO NAZIONALE DI GENETICA MOLECOLARE INGM
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (4)

ACE2-binding exposes the SARS-CoV-2 fusion peptide to broadly neutralizing coronavirus antibodies

Author(s): Low, J. S., Jerak, J., Tortorici, M. A., McCallum, M., Pinto, D., Cassotta, A., Foglierini, M., Mele, F., Abdelnabi, R., Weynand, B., Noack, J., Montiel-Ruiz, M., Bianchi, S., Benigni, F., Sprugasci, N., Joshi, A., Bowen, J. E., Stewart, C., Rexhepaj, M., Walls, A. C., Jarrossay, D., Morone, D., Paparoditis, P., Garzoni, C., Ferrari, P., Ceschi, A., Neyts, J. Purcell, L. A., Snell, G., Corti, D.,
Published in: Science, Issue 2022 Aug 12;377(6607):735-742, 2022, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abq2679

Different classes of genomic inserts contribute to human antibody diversity

Author(s): Lebedin, M., Foglierini, M., Khorkova, S., Vazquez Garcia, C., Ratswohl, C., Davydov, A. N., Turchaninova, M. A., Daubenberger, C., Chudakov, D. M., Lanzavecchia, A., de la Rosa, K.
Published in: PNAS, Issue 2022, vol 119, e2205470119, 2022, ISSN 1091-6490
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2205470119

Structural basis of malaria RIFIN binding by LILRB1-containing antibodies

Author(s): Yiwei Chen, Kai Xu, Luca Piccoli, Mathilde Foglierini, Joshua Tan, Wenjie Jin, Jason Gorman, Yaroslav Tsybovsky, Baoshan Zhang, Boubacar Traore, Chiara Silacci-Fregni, Claudia Daubenberger, Peter D. Crompton, Roger Geiger, Federica Sallusto, Peter D. Kwong, Antonio Lanzavecchia
Published in: Nature, Issue 31 March 2021 592, 2021, Page(s) 639-643, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-021-03378-6

Clonal structure, stability and dynamics of human memory B cells and circulating plasmablasts

Author(s): Phad, G. E., Pinto, D., Foglierini, M., Akhmedov, M., Rossi, R. L., Malvicini, E., Cassotta, A., Fregni, C. S., Bruno, L., Sallusto, F., Lanzavecchia, A.
Published in: Nature Immunology, Issue 2022, vol 23: 1076-1085, 2022, ISSN 1529-2916
Publisher: Nature Publishing Group
DOI: 10.1038/s41590-022-01230-1