MALDI-TOF mass spectrometry metabolite screening assays for drug discovery in human disease

Project Information

HTS MALDI-TOF MDD

Grant agreement ID: 890296

DOI 10.3030/890296

Project closed

EC signature date 20 March 2020

Start date 1 April 2020

End date 12 July 2022

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 212 933,76

EU contribution € 212 933,76

Coordinated by

UNIVERSITY OF NEWCASTLE UPON TYNE
United Kingdom

Publications

Peer reviewed articles (2)

Delayed induction of type I and III interferons mediates nasal epithelial cell permissiveness to SARS-CoV-2

Author(s): Catherine F. Hatton, Rachel A. Botting, Maria Emilia Dueñas, Iram J. Haq, Bernard Verdon, Benjamin J. Thompson, Jarmila Stremenova Spegarova, Florian Gothe, Emily Stephenson, Aaron I. Gardner, Sandra Murphy, Jonathan Scott, James P. Garnett, Sean Carrie, Jason Powell, C. M. Anjam Khan, Lei Huang, Rafiqul Hussain, Jonathan Coxhead, Tracey Davey, A. John Simpson, Muzlifah Haniffa, Sophie Hambleton,
Published in: Nature Communications, Issue 12, 2021, Page(s) 7092, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27318-0

A Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Assay Identifies Nilotinib as an Inhibitor of Inflammation in Acute Myeloid Leukemia

Author(s): José Luis Marín-Rubio*, Rachel E. Peltier-Heap, Maria Emilia Dueñas, Tiaan Heunis, Abeer Dannoura, Joseph Inns, Jonathan Scott, A. John Simpson, Helen J. Blair, Olaf Heidenreich, James M. Allan, Jessica E. Watt, Mathew P. Martin, Barbara Saxty, and Matthias Trost*
Published in: Journal of Medical Chemistry, Issue 00222623, 2022, ISSN 0022-2623
Publisher: American Chemical Society
DOI: 10.1021/acs.jmedchem.2c00671