New biological insight into stress-related anxiety
Everyday stress may have a different impact on people, and some experience pathological responses, such as anxiety and depression. It is well established that anxiety correlates with the response of dopamine neurons to the stress-induced corticotropin-releasing hormone. The EU-funded MotiVTA project will work on two emerging neuronal pathways that also influence anxiety. The balance between these pathways seems to affect dopamine release and drive motivation in response to stress. Researchers will employ a variety of approaches to monitor and manipulate the activity of these pathways and elucidate their engagement in anxiety response.