Microneedle-assisted nanovector skin patch for immunomodulation of the inflammatory response upon occurrence of myocardial infarction injury (MiNeMi)

Project description

Immune system modulation after myocardial infarction

Current treatment strategies for ischaemic heart disease only ameliorate symptoms. The EU-funded MiNeMI project is working on a novel immunomodulatory approach that aims to regulate inflammation and promote heart regeneration after myocardial infarction. Researchers are developing a non-invasive microneedle-based skin patch loaded with both immunomodulatory and biological molecules. The idea is to release these therapeutics into the dermal layer of the skin where a reservoir of immune cells resides. The efficacy and safety of the MiNeMI approach will be tested in vitro and in an animal model of cardiac ischaemia.

Fields of science

• natural sciences › biological sciences › biochemistry › biomolecules › proteins
• natural sciences › biological sciences › cell biology
• medical and health sciences › basic medicine › immunology
• medical and health sciences › clinical medicine › cardiology › cardiovascular diseases

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019

See other projects for this call

Funding Scheme

MSCA-IF - Marie Skłodowska-Curie Individual Fellowships (IF)

Coordinator

HELSINGIN YLIOPISTO

Net EU contribution

€ 190 680,96

Address

Yliopistonkatu 3
00014 Helsingin Yliopisto
Finland

Region

Manner-Suomi › Helsinki-Uusimaa › Helsinki-Uusimaa

Activity type

Higher or Secondary Education Establishments

Links

Other funding

€ 0,00