Unconventional NMDAR signaling theory for Fragile X Syndrome

Project Information

METAFRAX

Grant agreement ID: 892837

DOI

10.3030/892837

Project closed

EC signature date 24 March 2020

Start date 1 February 2021

End date 11 January 2025

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 244 385,28

EU contribution

€ 244 385,28

Coordinated by

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Conference proceedings (4)

NMDA receptors in synaptic plasticity: more than coincidence

Author(s): S. RANNIO, A. THOMAZEAU, J. A. BROCK, B. KO, G. MOFFAT, P. J. SJÖSTRÖM
Published in: 2022
Publisher: SFN

Presynaptic NMDA receptors signal non-ionotropically in neocortical STDP

Author(s): Aurore Thomazeau, Sabine Rannio, Jennifer Brock, Per Jesper Sjöström
Published in: 2023
Publisher: CAN meeting

Distinct roles of axonal and dendritic NMDARs in synaptic release and plasticity

Author(s): Distinct roles of axonal and dendritic NMDARs in synaptic release and plasticity
Published in: 2023
Publisher: CAN meeting

Presynaptic NMDA receptors signal metabotropically in neocortical STDP

Author(s): Aurore Thomazeau, Jennifer Brock, Per Jesper Sjöström
Published in: 2022
Publisher: CAN meeting

Non-peer reviewed articles (1)

Neocortical Layer-5 tLTD Relies on Non-Ionotropic Presynaptic NMDA Receptor Signaling

Author(s): Aurore Thomazeau, Sabine Rannio, Jennifer A. Brock, Hovy Ho-Wai Wong, P. Jesper Sjöström
Published in: biorXiv, 2025, ISSN 2692-8205
Publisher: bioRkiv
DOI: 10.1101/2025.02.07.637179

Peer reviewed articles (1)

Non-ionotropic signaling through the NMDA receptor GluN2B carboxy-terminal domain drives dendritic spine plasticity and reverses fragile X phenotypes

Author(s): Stephanie A. Barnes, Aurore Thomazeau, Peter S.B. Finnie, Maxwell J. Heinrich, Arnold J. Heynen, Noburu H. Komiyama, Seth G.N. Grant, Frank S. Menniti, Emily K. Osterweil, Mark F. Bear
Published in: Cell Reports, 2025, Page(s) 115311, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2025.115311