Heparin and heparin proteoglycan-mimetics activate platelets via PEAR1 and PI3Kβ
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Author(s):
Caroline Kardeby, Alice Evans, Joana Campos, Afraa Moosa Al-Wahaibi, Christopher W. Smith, Alexandre Slater, Eleyna M. Martin, Sonia Severin, Alexander Brill, Gunnar Pejler, Yi Sun, Steve P. Watson
Published in:
Journal of Thrombosis and Haemostasis, 2022, ISSN 1538-7836
Publisher:
Elsevier Inc.
DOI:
10.1016/j.jtha.2022.10.008
Is the endogenous ligand for PEAR1 a proteoglycan: clues from the sea
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Author(s):
Caroline Kardeby, Foteini-Nafsika Damaskinaki, Yi Sun, Stephen P Watson
Published in:
Platelets, 2021, ISSN 0953-7104
Publisher:
Taylor & Francis
DOI:
10.1080/09537104.2020.1863938
Antiplatelet drugs block platelet activation by VITT patient serum
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Author(s):
Christopher W. Smith, Samantha J. Montague, Caroline Kardeby, Ying Di, Gillian C. Lowe, William A. Lester, Steve P. Watson, and Phillip L. R. Nicolson
Published in:
Blood, 2021, ISSN 0006-4971
Publisher:
American Society of Hematology
DOI:
10.1182/blood.2021012277