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Chimeric antigen receptor (CAR) T-cell therapy against solid tumors by targeting the vasculature


Directing CAR T cells towards the tumor vasculature for the treatment of solid tumors

Author(s): Parvin Akbari, Afroditi Katsarou, Roxanna Daghighian, Lotte W. H. G. van Mil, Elisabeth J. M. Huijbers, Arjan W. Griffioen, Judy R. van Beijnum
Published in: BBA - Reviews on Cancer, 2022, ISSN 0304-419X
Publisher: Elsevier BV
DOI: 10.1016/j.bbcan.2022.188701

The tumor vasculature an attractive CAR T cell target in solid tumors

Author(s): Parvin Akbari, Elisabeth J. M. Huijbers, Maria Themeli, Arjan W. Griffioen, Judy R. van Beijnum
Published in: Angiogenesis, 2019, ISSN 0969-6970
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10456-019-09687-9

Extracellular vimentin mimics VEGF and is a target for anti-angiogenic immunotherapy

Author(s): Judy R. van Beijnum, Elisabeth J. M. Huijbers, Karlijn van Loon, Athanasios Blanas, Parvin Akbari, Arno Roos, Tse J. Wong, Stepan S. Denisov, Tilman M. Hackeng, Connie R. Jimenez, Patrycja Nowak-Sliwinska and Arjan W. Griffioen
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-30063-7

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