Applying human lung tissue models to develop a personalised treatment for critically ill

Project Information

ALGORITM

Grant agreement ID: 895134

DOI

10.3030/895134

Project closed

EC signature date 18 November 2020

Start date 1 April 2021

End date 31 March 2023

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 212 933,76

EU contribution

€ 212 933,76

Coordinated by

THE QUEEN'S UNIVERSITY OF BELFAST
United Kingdom

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (2)

Mesenchymal stromal cells-derived extracellular vesicles reprogramme macrophages in ARDS models through the miR-181a-5p-PTEN-pSTAT5-SOCIS1 axis

Author(s): Yue Su, Johnatas Dutra Silva, Declan Doherty, David A Simpson, Daniel J Weiss, Sara Rolandsson-Enes, Daniel F McAuley, Cecilia M O'Kane, Derek P Brazil, Anna D Krasnodembskaya
Published in: Thorax, 2023, ISSN 1468-3296
Publisher: British Thoracic Society and BMJ
DOI: 10.1136/thoraxjnl-2021-218194

Nebulised mesenchymal stem cell derived extracellular vesicles ameliorate E. coli induced pneumonia in a rodent model

Author(s): Hector Gonzalez, Sean McCarthy, Claire Masterson, Declan Byrnes, Ignacio Sallent, Emma Horan, Stephen J. Elliman, Gabriele Vella, Adriele P. Mello, Johnatas D. Silva, Anna D. Krasnodembskaya, Ronan MacLoughlin, John G. Laffey & Daniel O’Toole
Published in: Stem Cell Research & Therapy, 2023, ISSN 1757-6512
Publisher: BioMed Central
DOI: 10.1186/s13287-023-03385-6

Conference proceedings (2)

Mesenchymal stromal cell-derived extracellular vesicles attenuate metabolic changes inpre-clinical models of ARDS through mitochondrial transfer

Author(s): Johnatas Silva; Declan Doherty; Catherine McClintock; Daniel McAuley; Cecilia O’Kane; Anna D. Krasnodembskaya
Published in: Journal of Extracellular Vesicles, 2022, ISSN 2001-3078
Publisher: Wiley Online Library
DOI: 10.1002/jev2.12224

MSC-DERIVED EXTRACELLULAR VESICLES MODULATE METABOLIC ALTERATIONS IN HUMAN PULMONARY ENDOTHELIAL AND EPITHELIAL CELLS IN THE MODELS OF ARDS

Author(s): J.D. Silva, D. Doherty, C. McClintock, D. McAuley, C. O’Kane, A. Krasnodembskaya
Published in: Cytotherapy, 2022, ISSN 1465-3249
Publisher: Elsevier
DOI: 10.1016/s1465-3249(22)00145-1