The role of ATP in the central nervous system
Adenosine triphosphate (ATP) is the energy currency of all cells, essential for driving many living processes. The EU-funded COST-ATP project aims to investigate the role of ATP in neurotransmitter vesicles in excitatory and inhibitory synapses of the central nervous system. To this end, scientists plan to interfere with the vesicular nucleotide carrier (VNUT) implicated in ATP transport without affecting the overall cellular levels of ATP. The emergence of ATP as a regulator of neuronal transmission opens new avenues for the identification of new pharmacological targets for the treatment of neurological, psychiatric and cardiovascular diseases.