ARBOVIRUS SKIN INFECTION MODELLING FOR MORE ACCURATE VIRAL PATHOGENESIS

Project description

An engineered skin model for studying Dengue virus infection

Dengue is a viral disease transmitted by arthropods such as mosquitoes, and it poses a significant threat in tropical and subtropical regions of the world. There is a lack of experimental systems for studying Dengue arbovirus pathogenesis, hampering biomedical advances. Scientists of the EU-funded VirIVITES project propose to develop an in vitro Dengue arbovirus infection model based on tissue-engineered human skin. The model will comprise immune cells, sensory nerve cells and naturally infected mosquitoes. It will serve to investigate infection and cell responses to the Dengue arbovirus. Using this model, scientists hope to develop new strategies for preventing or treating arbovirus-associated neurological symptoms.

Fields of science

• medical and health sciences › health sciences › infectious diseases › RNA viruses
• natural sciences › biological sciences › microbiology › virology
• medical and health sciences › medical biotechnology › cells technologies › stem cells
• social sciences › economics and business › business and management › employment
• natural sciences › biological sciences › molecular biology

Programme(s)

• H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions Main Programme
• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019

See other projects for this call

Funding Scheme

MSCA-IF-EF-RI - RI – Reintegration panel

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

Net EU contribution

€ 196 707,84

Address

Rue Michel Ange 3
75794 Paris
France

Region

Ile-de-France › Ile-de-France › Paris

Activity type

Research Organisations

Links

Other funding

€ 0,00