ARBOVIRUS SKIN INFECTION MODELLING FOR MORE ACCURATE VIRAL PATHOGENESIS

Project description

An engineered skin model for studying Dengue virus infection

Dengue is a viral disease transmitted by arthropods such as mosquitoes, and it poses a significant threat in tropical and subtropical regions of the world. There is a lack of experimental systems for studying Dengue arbovirus pathogenesis, hampering biomedical advances. Scientists of the EU-funded VirIVITES project propose to develop an in vitro Dengue arbovirus infection model based on tissue-engineered human skin. The model will comprise immune cells, sensory nerve cells and naturally infected mosquitoes. It will serve to investigate infection and cell responses to the Dengue arbovirus. Using this model, scientists hope to develop new strategies for preventing or treating arbovirus-associated neurological symptoms.

Fields of science

• natural sciences › biological sciences › molecular biology
• natural sciences › biological sciences › microbiology › virology
• medical and health sciences › health sciences › infectious disease › RNA virus
• medical and health sciences › medical biotechnology › cells technologies › stem cells

Programme(s)

• H2020-EU.1.3.2. - Nurturing excellence by means of cross-border and cross-sector mobility

Topic(s)

• MSCA-IF-2019 - Individual Fellowships

Call for proposal

H2020-MSCA-IF-2019
See other projects for this call

Funding Scheme

MSCA-IF-EF-RI - RI – Reintegration panel

Coordinator

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS

Address

Rue Michel Ange 3
75794 Paris
France

Activity type

Other

EU contribution

€ 196 707,84