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Understanding resistance to immune checkpoint inhibitors by mapping the tumor-host ecosystem at single-cell resolution

Publications

Evolutionary predictability of genetic versus nongenetic resistance to anticancer drugs in melanoma

Author(s): Oskar Marin-Bejar 1 , Aljosja Rogiers 1 , Michael Dewaele 1 , Julia Femel 2 , Panagiotis Karras 1 , Joanna Pozniak 1 , Greet Bervoets 1 , Nina Van Raemdonck 1 , Dennis Pedri 1 , Toon Swings 3 , Jonas Demeulemeester 4 , Sara Vander Borght 5 , Stefan Lehnert 6 , Francesca Bosisio 7 , Joost J van den Oord 7 , Isabelle Vanden Bempt 6 , Diether Lambrechts 8 , Thierry Voet 9 , Oliver B
Published in: Cancer Cell, 2021, ISSN 1535-6108
Publisher: Cell Press
DOI: 10.1016/j.ccell.2021.05.015

A TCF4/BRD4-dependent regulatory network confers cross-resistance to targeted and immune checkpoint therapy in melanoma

Author(s): Joanna Pozniak, Dennis Pedri, Ewout Landeloos, Yannick Van Herck, Asier Antoranz, Panagiotis Karras, Ada Nowosad, Samira Makhzami, Greet Bervoets, Michael Dewaele, Lukas Vanwynsberghe, Sonia Cinque, Sam Kint, Katy Vandereyken, Thierry Voet, Frank Vernaillen, Wim Annaert, Diether Lambrechts, Veerle Boecxstaens, Joost van den Oord, Francesca Bosisio, Eleonora Leucci, Florian Rambow, Ol
Published in: 2022
Publisher: bioRxiv
DOI: 10.1101/2022.08.11.502598

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