Validation and commercial application of organ-on-chip platform
The organ-on-chip technology defines a physiological organ biomimetic system built on a microfluidic chip. A combination of cell biology, engineering, biomaterial technology and the microenvironment of the chip simulates tissue interfaces and organ mechanical stimulations. This technology can predict drug responses and environmental effects but is staying behind due to a lack of standardisation in chip manufacturing, lack of automation, which limits the throughput capabilities, and lack of support for sensor integration. The EU-funded open-TOP proof-of-concept project aims to commercialise the application of the organ-on-chip platform previously developed at the University of Twente (the Netherlands) and designed to overcome the current hurdles.
Call for proposal
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