Understanding the role of lysosomes in the intercellular TNT-mediated spreading of α-synuclein and the impact of lysosomal dysfunction

Project Information

LySyT

Grant agreement ID: 897378

DOI 10.3030/897378

Project closed

EC signature date 11 March 2020

Start date 1 December 2020

End date 30 November 2022

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost € 184 707,84

EU contribution € 184 707,84

Coordinated by

INSTITUT PASTEUR
France

Publications

Peer reviewed articles (1)

α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes

Author(s): Dilsizoglu Senol, Aysegul; Samarani, Maura; Syan, Sylvie; Guardia, Carlos M.; Nonaka, Takashi; Liv, Nalan; Latour-Lambert, Patricia; Hasegawa, Masato; Klumperman, Judith; Bonifacino, Juan S.; Zurzolo, Chiara
Published in: PLOS Biology, Issue 15449173, 2021, ISSN 1544-9173
Publisher: Public Library of Science
DOI: 10.1371/journal.pbio.3001287