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Screening of inFlammation to enable personalized Medicine

Project description

Complement factor H-related proteins and their role in pathogenesis

Complement factor H (FH) and FH-related (FHR) proteins are associated with systemic and organ-specific pathologies including impaired defense against infections and incurable renal, eye and autoimmune diseases. While the biological function of FH is well-defined, the function of the other six highly homologous FHR proteins is mostly unknown, as is their role in the disease-specific pathogenic mechanisms. The EU-funded SciFiMed project will study the FH family proteins' contributions in health and disease aiming to obtain proof-of-principle for a multiplex detection system to simultaneously quantify and analyse the functional activity of all seven proteins in patient samples. This high-impact project will enable new product developments and provide new perspectives for patient treatments.

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-01

Coordinator

PHILIPPS UNIVERSITAET MARBURG
Net EU contribution
€ 778 750,00
Address
Biegenstrasse 10
35037 Marburg
Germany

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Region
Baden-Württemberg Stuttgart Stuttgart, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00

Participants (8)

UNIVERSITAET REGENSBURG
Germany
Net EU contribution
€ 657 426,25
Address
Universitatsstrasse 31
93053 Regensburg

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Region
Bayern Oberpfalz Regensburg, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
UNIVERSIDAD COMPLUTENSE DE MADRID
Spain
Net EU contribution
€ 334 875,00
Address
Avenida De Seneca 2
28040 Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
Stichting Sanquin Bloedvoorziening
Netherlands
Net EU contribution
€ 566 250,00
Address
Plesmanlaan 125
1006 AN Amsterdam

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Region
West-Nederland Noord-Holland Groot-Amsterdam
Activity type
Research Organisations
Other funding
€ 0,00
EOTVOS LORAND TUDOMANYEGYETEM
Hungary
Net EU contribution
€ 350 000,00
Address
Egyetem Ter 1-3
1053 Budapest

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Region
Közép-Magyarország Budapest Budapest
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
ACADEMISCH ZIEKENHUIS GRONINGEN
Netherlands
Net EU contribution
€ 328 750,00
Address
Hanzeplein 1
9713 GZ Groningen

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Region
Noord-Nederland Groningen Overig Groningen
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
Hycult biotechnology bv
Netherlands
Net EU contribution
€ 190 000,00
Address
Frontstraat 2a
5405 PB Uden

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Zuid-Nederland Noord-Brabant Noordoost-Noord-Brabant
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 132 000,00
MICROCOAT BIOTECHNOLOGIE GMBH
Germany
Net EU contribution
€ 353 750,00
Address
Am Neuland 3
82347 Bernried

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Bayern Oberbayern Weilheim-Schongau
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
KLINIKUM DER UNIVERSITAET REGENSBURG

Participation ended

Germany
Net EU contribution
€ 0,00
Address
Frans Josef Strauss Allee 11
93053 Regensburg
Region
Bayern Oberpfalz Regensburg, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00