Screening of inFlammation to enable personalized Medicine

Project Information

SciFiMed

Grant agreement ID: 899163

DOI 10.3030/899163

EC signature date 26 May 2020

Start date 1 January 2021

End date 31 December 2024

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost € 3 691 801,25

EU contribution € 3 559 801,25

Coordinated by

PHILIPPS UNIVERSITAET MARBURG
Germany

Deliverables

Documents, reports (3)

LFA feasibility

Report on first 7pley LFA feasibilty study

Press release 1

Kick of Press release

Description dynamic range LFAs

Report dynamic ranges for all singleanalyte LFA

Websites, patent fillings, videos etc. (3)

Webpage, Logo and updates

Webpage proposed domain scifimedeu SciFiMed logo and continuous updates

SciFiMed Flyer
SciFiMed Video

SciFiMed introduction video

Publications

Peer reviewed articles (12)

A Family Affair: Addressing the Challenges of Factor H and the Related Proteins

Author(s): Felix Poppelaars, Elena Goicoechea de Jorge, Ilse Jongerius, Antje J. Baeumner, Mark-Steven Steiner, Mihály Józsi, Erik J. M. Toonen, Diana Pauly
Published in: Frontiers in Immunology, Issue 12, 2021, ISSN 1664-3224
Publisher: Lausanne: Frontiers Media S.A., 2010-
DOI: 10.3389/fimmu.2021.660194

The human factor H protein family – an update

Author(s): Sándor, Noémi, Schneider, Andrea E., Matola, Alexandra T., Barbai, Veronika H., Bencze, Dániel, Hammad, Hani Hashim, Papp, Alexandra, Kövesdi, Dorottya, Uzonyi, Barbara, Józsi, Mihály
Published in: Frontiers In Immunology, Issue Volume 15 - 2024, 2024, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/fimmu.2024.1135490

Complement Factor H-Related Proteins FHR1 and FHR5 Interact With Extracellular Matrix Ligands, Reduce Factor H Regulatory Activity and Enhance Complement Activation.

Author(s): Alexandra Papp; Krisztián Papp; Barbara Uzonyi; Marcell Cserhalmi; Ádám I. Csincsi; Zsóka Szabó; Zsófia Bánlaki; David Ermert; Zoltán Prohászka; Anna Erdei; Viviana P. Ferreira; Anna M. Blom; Mihály Józsi
Published in: Frontiers in Immunology, Issue 13, 2022, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2022.845953

Editorial: Updates on the complement system in kidney diseases

Author(s): Bulla R., Józsi M
Published in: Frontiers in Immunology, Issue 14, 2023, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2023.1196487

The Factor H protein family: The switchers of the complement alternative pathway

Author(s): Laura Lucientes‐Continente; Bárbara Márquez‐Tirado; Elena Goicoechea de Jorge
Published in: Immunological Reviews, Issue 313(1), 2023, Page(s) 25-45, ISSN 0105-2896
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/imr.13166

The Contribution of Complement to the Pathogenesis of IgA Nephropathy: Are Complement-Targeted Therapies Moving from Rare Disorders to More Common Diseases?

Author(s): Felix Poppelaars; Bernardo Faria; Wilhelm Schwaeble; Mohamed R. Daha
Published in: Journal of Clinical Medicine, Issue Vol 10, Iss 4715, p 4715 (2021), 2021, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.17863/cam.77005

Editorial: Function and Dysfunction of Complement Factor H

Author(s): Mihály Józsi, Pauli Nigel Barlow and Seppo Meri
Published in: Frontiers in Immunology, Issue 12, 2022, ISSN 1664-3224
Publisher: Frontiers S.A.
DOI: 10.3389/fimmu.2021.831044

Factor H-Related Protein 1 Drives Disease Susceptibility and Prognosis in C3 Glomerulopathy.

Author(s): Bárbara Márquez-Tirado; Josué Gutiérrez-Tenorio; Agustín Tortajada; Laura Lucientes Continente; Fernando Caravaca-Fontán; Talat H. Malik; Raquel Roldán Montero; Sandra Elías; Ana Saiz Gonzalez; Gema Fernández-Juarez; Pilar Sánchez-Corral; Matthew C. Pickering; Manuel Praga; Santiago Rodríguez de Córdoba; Elena Goicoechea de Jorge
Published in: Journal of the American Society of Nephrology, Issue Jun;33(6), 2022, Page(s) 1137-1153, ISSN 1046-6673
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1681/asn.2021101318

Evaluating the clinical utility of measuring levels of factor H and the related proteins

Author(s): Pratiti Banerjee; Bert R.J. Veuskens; Elena Goicoechea de Jorge; Mihály Józsi; Antje J. Baeumner; Mark-Steven Steiner; Richard B. Pouw; Erik J.M. Toonen; Diana Pauly; Felix Poppelaars
Published in: Molecular Immunology, Issue 151, 2022, ISSN 0161-5890
Publisher: Pergamon Press
DOI: 10.1016/j.molimm.2022.08.010

Complement Factor H Family Proteins Modulate Monocyte and Neutrophil Granulocyte Functions

Author(s): Éva Kárpáti, Mariann Kremlitzka, Noémi Sándor, Dávid Hajnal, Andrea E. Schneider and Mihály Józsi
Published in: Frontiers in Immunology, Issue 12:660852, 2021, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.660852

Pitfalls in complement analysis: A systematic literature review of assessing complement activation

Author(s): Ricardo J. M. G. E. Brandwijk, Marloes A. H. M. Michels, Mara van Rossum, Aline H. de Nooijer, Per H. Nilsson, Wieke C. C. de Bruin and Erik J. M. Toonen
Published in: Frontiers in Immunology, Issue 13, 2022, ISSN 1664-3224
Publisher: Frontiers S.A.
DOI: 10.3389/fimmu.2022.1007102

Complement Factor H-Related 3 Enhanced Inflammation and Complement Activation in Human RPE Cells

Author(s): Nicole Schäfer, Anas Rasras, Delia M. Ormenisan, Sabine Amslinger, Volker Enzmann, Herbert Jägle and Diana Pauly
Published in: Frontiers in Immunology, Issue 12:769242, 2021, ISSN 1664-3224
Publisher: Frontiers Media S.A
DOI: 10.3389/fimmu.2021.769242