Photodynamic therapy triggered by spectral scanner CT: an efficient tool for cancer treatment

Project Information

SCANnTREAT

Grant agreement ID: 899549

DOI

10.3030/899549

Project closed

EC signature date 26 May 2020

Start date 1 September 2020

End date 29 February 2024

Funded under

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Total cost

€ 2 999 955,00

EU contribution

€ 2 999 955,00

Coordinated by

UNIVERSITE LYON 1 CLAUDE BERNARD
France

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Deliverables

Documents, reports (16)

Final Version - Hybrid Probe for imaging and Treatment

Update of D1.3 Characterisation and finalisation of all the characteristics of the probe (scintillation, ROS generation) (T1.3)

Final Version - Surface modification of the scintillating probe

Update of D1.2 with information on the evolution of the scintillating characteristics the probe (T1.2)

Final Version - Intracellular diffusion of nanohybrids

Update of D21 Report containing a description of the characteristics of the quantitative intracellular localisation of nanohybrids in 2D by Xray fluorescence T21

Collection of the dissemination material of the project

All the dissemination material produced in the frame of SCANnTREAT (scientific articles, posters and support material for dissemination in Internation conferences...) will be gathered in this report

Final Version - Response of healthy tissues

Update of D2.3 - Final Report describing the response of healthy tissues to SCANnTREAT technology depending on doses, energies and concentrations of nanohybrids (T2.2)

Initial Version - Response of tumors

First version of the report describing the response of tumor models to SCANnTREAT technology depending on doses, energies and concentrations of nanohybrids (T2.3)

Initial Version - Hybrid probe for imaging and treatment

Characterisation of the probe for imaging and treatment Task 13

Initial Version - Response of healthy tissues

First version of the report describing the response of healthy tissues to SCANnTREAT technology depending on doses, energies and concentrations of nanohybrids (T2.2)

Hybrid probe with optimized scintillating properties and imaging for in vivo

Description of basic particles production protocol

Report on Kick-off meeting

Report containing the agenda and the minutes of the Kick-off meeting

Final Version - Response of tumors

Update of D2.4 - Final report describing the response of tumor models to SCANnTREAT technology depending on doses, energies and concentrations of nanohybrids (T2.3)

Collection of communication's supporting material

Collection of the communication supports produced during SCANnTREAT for the different kind of target audiences

Final review report

Conclusion report of the SCANnTREAT project

Report on consortium attendance to conferences to disseminate SCANnTREAT outcomes

Listing and description of the conferences to which the members of SCANnTREAT attended and ways poster conferences through which SCANnTREAT results have been disseminated Task 41

Initial Version - Intracellular diffusion of nanohybrids

First version of the report containing a description of the characteristics of the quantitative intracellular localisation of nanohybrids in 2D by Xray fluorescence T21

Initial Version - Surface modification of the scintillating probe

Update of D11 with information on the evolution of the scintillating characteristics the probe T12

Websites, patent fillings, videos etc. (1)

Project Website and logo

report about the launchin of the SCANnTREAT website and its content description of the logo

Publications

Peer reviewed articles (2)

DNA Double-Strand Breaks Induced in Human Cells by Twelve Metallic Species: Quantitative Inter-Comparisons and Influence of the ATM Protein

Author(s): Muriel Viau, Laurène Sonzogni, Mélanie L. Ferlazzo, Elise Berthel, Sandrine Pereira, Larry Bodgi, Adeline Granzotto, Clément Devic, Béatrice Fervers, Laurent Charlet, Nicolas Foray
Published in: Biomolecules, Issue 11/10, 2021, Page(s) 1462, ISSN 2218-273X
Publisher: Biomokecules
DOI: 10.3390/biom11101462

Surface modification effect on contrast agent efficiency for X-ray based spectral photon-counting scanner/luminescence imaging: from fundamental study to <i>in vivo</i> proof of concept

Author(s): Loic Cuau, Pia Akl, A. Gautheron, Angèle Houmeau, Frédéric Chaput, Ala Yaromina, Ludwig Dubois, Philippe Lambin, Szilvia Karpati, Stephane Parola, B. Rezaeifar, Jean-Baptiste Langlois, Salim A. Si-Mohamed, Bruno Montcel, Philippe Douek, Frederic Lerouge
Published in: Nanoscale, Issue 16, 2024, Page(s) 2931-2944, ISSN 2040-3364
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3nr03710j