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Immunological incompatibility as a basis for cancer curing and vaccination

Deliverables

Web site social media and logo

Launch of the project visual identity logo and other grapic elements the project website and social media channels Twitter account and LinkedIn page

Communication materials

Communication materials will include the project flyer a short presentation video an official power point presentation of the project a rollup poster

First set of potentially useful monoclonal anti-HLA-A antibodies

Description of a first set of potentially useful monoclonal antiHLAA antibodies capable of reacting against the alloHLA antigens expressed on the surface of tumour cells

Synthesis and characterization of NPs

NPs will be prepared following solgel routes and fully characterized using different techniques including electron microscopy powder xray diffraction porosimetry etc

Report on establishment of optimal collection, processing, storing and analysis of biological materials from patients

A report explaining the establishment of optimal collection processing storing and analysis of biological materials from pancreatic cancer patients

Production of transfection grade plasmid DNA (pDNA) to be used in T3.4 (assessment of pDNA effect in target cells)

Required amounts of pDNA will be produced following standard internal procedures

Constitution of the different management committees

The following committees will be formally constituted1 Project Management and Steering Committee PMSC 2 Scientific and Technical Committee STC3 Innovation and Exploitation Committee IXC4 Ethics Management Committee EMC

Data Management Plan

The Data Management Plan will provide the protocols to be followed in the management and treatment of data

Publications

A Comprehensive Transcriptional Signature in Pancreatic Ductal Adenocarcinoma Reveals New Insights into the Immune and Desmoplastic Microenvironments

Author(s): Irene Pérez-Díez, Zoraida Andreu Marta R Hidalgo, Carla Perpiñá-Clérigues, Lucía Fantín, Antonio Fernandez-Serra, María de la Iglesia-Vaya, José A Lopez-Guerrero, Francisco García-García
Published in: Cancers (Basel), Issue 2023 May 24;15(11):2887, 2023, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers15112887

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