Project description
Magnetic control of crystal formation could lead to new pharmaceuticals
Polymorphism, the ability of solid materials to exist in more than one crystalline arrangement of constituents, is sort of like the ability of proteins to exist in more than one conformational 3D shape, affecting functionality. More than 50 % of active pharmaceutical ingredients likely exist in more than one polymorphic form. The different forms can have different abilities to dissolve in certain solvents, different stabilities or flow characteristics and different drug efficacy, bioavailability, even toxicity. The EU-funded Eutomic project is building on its discovery of the ability to control polymorphism with strong magnetic fields. The project will enable scientists to pave the way for a successful university spin-off that will commercialise this potential to produce novel pharmaceuticals with new types of co-crystals.
Objective
EUTOMIC presents a completely new and unexpected idea sprung from the cradle of the EU Horizon2020 FET-Open grant ‘MagnaPharm’ which is concerned with the control of polymorphism in pharmaceuticals through the application of strong magnetic fields. The desire to control and constrain the growth of crystals using external stimuli in MagnaPharm led inexorably to the discovery of this new class of deep eutectics, using a sparingly stable synergistic solvent system as a vector for the spontaneous creation of new cocrystals in and of itself.
EUTOMIC proposes the support of the FET Innovation Launchpad to increase the investment readiness of this innovation towards a commercially attractive & sustainable university spin-off company, ‘Eutomic Ltd.’, EUTOMIC will foster the full exploration and exploitation of the novel materials being created from this new eutectic system.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.2. - EXCELLENT SCIENCE - Future and Emerging Technologies (FET)
MAIN PROGRAMME
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H2020-EU.1.2.1. - FET Open
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
CSA - Coordination and support action
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-FETOPEN-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
BS8 1QU BRISTOL
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.