Project description DEENESFRITPL Assessing the biological impact of nanomaterials Advances in nanotechnology over the years have led to the use of nanostructures in the research and biomedical fields. However, limited information is available on the life cycle of nanomaterials and their products. The scope of the EU-funded ICARUS-INAS project is to establish a service for assessing the biological impact and toxic effects of innovative nanostructures and record their life cycle. Using a combination of in vitro assays, omics technologies and toxicology studies, scientists will evaluate the human and environmental safety of specific nanocomposite products at all stages of their life cycle. The project will also offer the possibility to implement these methodologies at the customer's facilities upon request. Show the project objective Hide the project objective Objective The underlying innovation idea of this proposal (which is mainly addressing exploitation and dissemination activities), is the development of an Intregrated Nanostructures Assessment-Service for the biological impact analysis of nanostructures (INAS) combining toxicology and LCA studies for innovative materials. In the linked FET project ICARUS (Nr. 713514), a portfolio of LCA and nanosafety assessment tools was developed to determine environmental indicators, emissions and the mass/energy balance related to different materials/solutions adopted for the production of nc-alloys, as well as to ensure the safety of the new alloys at all stages of its life-cycle. This portfolio, including in vitro tests, rapid high-throughput tests and mechanistic toxicity projects applying omics technologies, will be offered for the assessment of the human and environmental safety of the customer´s product, which could be implemented in the customer´s facilities too when requested. The toxicology assessment will be tailored as well to the chemical-related impacts for which characterization factors (CFs) are necessary within the LCA analysis, allowing a full harmonization between the available toxicity data and the customer´s products life cycle, following the European Commision´s Joint Research Centre (EC-JRC) recommendations. In preparation of the INAS service, the exploitation, IPR and dissemination strategies will be defined and implemented in this project, based on in-depth market analysis, business planning and other exploitation-related activities. Fields of science medical and health sciencesbasic medicinetoxicology Programme(s) H2020-EU.1.2. - EXCELLENT SCIENCE - Future and Emerging Technologies (FET) Main Programme H2020-EU.1.2.1. - FET Open Topic(s) FETOPEN-03-2018-2019-2020 - FET Innovation Launchpad Call for proposal H2020-FETOPEN-2018-2020 See other projects for this call Sub call H2020-FETOPEN-2018-2019-2020-03 Funding Scheme CSA - Coordination and support action Coordinator UNIVERSIDAD DE BURGOS Net EU contribution € 100 000,00 Address HOSPITAL DEL REY 09001 Burgos Spain See on map Region Centro (ES) Castilla y León Burgos Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Total cost € 100 000,00