Project description
An intravenous patch for large venotomies
Various surgeries such as transcatheter heart valve procedures require large venotomies, holes in the femoral vein that provide access to the heart. However, these are difficult to close, leaving patients exposed to complications such as blood loss, infection and thrombosis. The EU-funded VENOCLOSE project proposes to address this unmet medical need by developing a patch-based product suitable for closing venotomies.The patch offers a matrix that supports wound healing and is based on existing and well-validated technology already in clinical use. It can be used intravenously, giving the surgeon the ability to seal vessels from the inside without the need for surgery.
Objective
Small venotomies (a hole in the vein to provide access for surgical procedures) are routinely made and closed using manual compression. As venotomies get bigger it becomes more difficult to close them, leading to complications (blood loss, haematoma, infection and thrombosis). Developments in transcatheter heart valve procedures and left atrial appendage occlusion requires large venotomies in the femoral vein to gain access to the heart. These large venotomies are difficult to close, leaving patients exposed to additional complications, pain and discomfort. Hence, there is a strong unmet medical need for effective methods to close venotomies.
Vivasure Medical Limited is a Irish R&D performing medical device company, established in 2008 and secured a total of €45M funds. Vivasure developed the patented PerQseal platform technology as effective method for large arterial and venous closures. PerQseal Venous is the world’s first absorbable patch-based closure product for large venotomy closure (over 8 mm). By delivering an intra-venous patch without surgery, a surgeon can seal vessels from inside while providing a matrix to support wound healing. PerQseal Venous is largely based on Vivasure’s already existing and well-validated PerQseal®Arterial product, used to close arterial vessels and already in clinical use.
Following clinical validation and preparation for EU and US wide commercialisation in the VENOCLOSE project, Vivasure will target the large and ever-growing venous closure market. Vivasure has successfully obtained ISO13485 Certification and CE certification for its arterial closure device, which will pave the way for PerQseal Venous. The company will leverage existing customer-base among cardiologists and distribution partner, contributing to a further de-risking of PerQseal Venous commercialisation. Obtaining €2.5M in EIC-Accelerator funding will accelerate the road to market for PerQseal Venous, and lead to direct revenue and employment growth at Vivasure.
Fields of science (EuroSciVoc)
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CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine angiology vascular diseases
- medical and health sciences clinical medicine surgery surgical procedures
- social sciences economics and business business and management employment
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.2.3. - INDUSTRIAL LEADERSHIP - Innovation In SMEs
MAIN PROGRAMME
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H2020-EU.3. - PRIORITY 'Societal challenges
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H2020-EU.2.1. - INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
SME-2 - SME instrument phase 2
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-EIC-SMEInst-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
H91 V3KP Galway
Ireland
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.