“tRNA actors” heterogeneity: a new identifier of cancer stem cells

Project Information

tRNAtoGO

Grant agreement ID: 948170

DOI

10.3030/948170

EC signature date 23 November 2020

Start date 1 February 2021

End date 31 January 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 499 988,00

EU contribution

€ 1 499 988,00

Coordinated by

UNIVERSITE DE LIEGE
Belgium

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Iron‐responsive element of Divalent metal transporter 1 (Dmt1) controls Notch‐mediated cell fates

Author(s): Judith Hounjet, Arjan J. Groot, Jolanda P. Piepers, Onno Kranenburg, Danny A. Zwijnenburg, Francesca A. Rapino, Jan B. Koster, Kim R. Kampen, Marc A. Vooijs
Published in: The FEBS Journal, Issue 290, 2024, Page(s) 5811-5834, ISSN 1742-464X
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/febs.16946

E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development

Author(s): Michela Di Michele, Aurore Attina, Pierre-François Roux, Imène Tabet, Sophie Laguesse, Javier Florido, Morane Houdeville, Armelle Choquet, Betty Encislai, Giuseppe Arena, Carlo De Blasio, Olivia Wendling, François-Xavier Frenois, Laura Papon, Lucille Stuani, Maryse Fuentes, Céline Jahannault Talignani, Mélanie Rousseau, Justine Guégan, Yoan Buscail, Pierrick Dupré, Henri-Alexandre Michaud,
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-55444-y

Ribosome exit tunnel electrostatics

Author(s): Marc Joiret , Frederic Kerff , Francesca Rapino , Pierre Close , Liesbet Geris
Published in: Phys Rev E., Issue 105(1-1):014409., 2022, ISSN 2470-0053
Publisher: American Physical Society
DOI: 10.1103/physreve.105.014409

Valine aminoacyl-tRNA synthetase promotes therapy resistance in melanoma

Author(s): Najla El-Hachem, Marine Leclercq, Miguel Susaeta Ruiz, Raphael Vanleyssem, Kateryna Shostak, Pierre-René Körner, Coralie Capron, Lorena Martin-Morales, Patrick Roncarati, Arnaud Lavergne, Arnaud Blomme, Silvia Turchetto, Eric Goffin, Palaniraja Thandapani, Ivan Tarassov, Laurent Nguyen, Bernard Pirotte, Alain Chariot, Jean-Christophe Marine, Michael Herfs, Francesca Rapino, Reuven Agami, Pierre
Published in: Nature Cell Biology, Issue 26, 2024, Page(s) 1154-1164, ISSN 1465-7392
Publisher: Nature Publishing Group
DOI: 10.1038/s41556-024-01439-2

Cracking the genetic code with neural networks.

Author(s): Joiret M, Leclercq M, Lambrechts G, Rapino F, Close P, Louppe G, Geris L.
Published in: Front Artif Intell., Issue 6;6:1128153, 2023, ISSN 2624-8212
Publisher: IOS Press BV
DOI: 10.3389/frai.2023.1128153

Wobble tRNA modification and hydrophilic amino acid patterns dictate protein fate.

Author(s): Rapino F, Zhou Z, Roncero Sanchez AM, Joiret M, Seca C, El Hachem N, Valenti G, Latini S, Shostak K, Geris L, Li P, Huang G, Mazzucchelli G, Baiwir D, Desmet CJ, Chariot A, Georges M, Close P.
Published in: Nat Commun., Issue 12(1):2170, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22254-5

A simple geometrical model of the electrostatic environment around the catalytic center of the ribosome and its significance for the elongation cycle kinetics

Author(s): Marc Joiret, Frederic Kerff, Francesca Rapino, Pierre Close, Liesbet Geris
Published in: Computational and Structural Biotechnology Journal, Issue 21, 2024, Page(s) 3768-3795, ISSN 2001-0370
Publisher: Elsevier BV
DOI: 10.1016/j.csbj.2023.07.016