Engineering antibodies in B cells using endogenous AID activity

Project Information

AutoEngineering

Grant agreement ID: 948464

DOI

10.3030/948464

EC signature date 29 October 2020

Start date 1 July 2021

End date 30 June 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 489 500,00

EU contribution

€ 1 489 500,00

Coordinated by

MAX DELBRUECK CENTRUM FUER MOLEKULARE MEDIZIN IN DER HELMHOLTZ-GEMEINSCHAFT (MDC)
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (3)

Discriminating promiscuous from target‐specific autoantibodies in COVID‐19

Author(s): Mikhail Lebedin; Clara Vázquez García; Lisa Spatt; Christoph Ratswohl; Charlotte Thibeault; Lennard Ostendorf; Tobias Alexander; Friedemann Paul; Leif Erik Sander; Florian Kurth; Kathrin de la Rosa
Published in: European Journal of Immunology, Issue 53(5):e2250210, 2023, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202250210

A design strategy to generate a SARS‐CoV‐2 RBD vaccine that abrogates ACE2 binding and improves neutralizing antibody responses

Author(s): Christoph Ratswohl; Clara Vázquez García; Ata ul Wakeel Ahmad; Hannes Gonschior; Mikhail Lebedin; Casper Ewijn Silvis; Lisa Spatt; Cathrin Gerhard; Martin Lehmann; Leif E. Sander; Florian Kurth; Simon Olsson; Kathrin de la Rosa
Published in: European Journal of Immunology, Issue 53(10):e2350408, 2023, ISSN 0014-2980
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/eji.202350408

Different classes of genomic inserts contribute to human antibody diversity

Author(s): Mikhail Lebedin, Mathilde Foglierini, Svetlana Khorkova, Clara Vazquez Garcıa, Christoph Ratswohl, Alexey N. Davydov, Maria A. Turchaninova, Claudia Daubenberger, Dmitriy M. Chudakov, Antonio Lanzavecchia, and Kathrin de la Rosa
Published in: PNAS, Issue 119(36):e2205470119, 2022, ISSN 1091-6490
Publisher: PNAS
DOI: 10.1073/pnas.2205470119