Targeting the crosstalk of lipid and glucose metabolism to stop cancer-associated wasting

Project Information

StopWaste

Grant agreement ID: 949017

DOI

10.3030/949017

EC signature date 6 November 2020

Start date 1 May 2021

End date 30 April 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 411 051,00

EU contribution

€ 1 411 051,00

Coordinated by

HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Development of a peptide drug restoring AMPK and adipose tissue functionality in cancer cachexia

Author(s): Honglei Ji, Felix Englmaier, Pauline Morigny, Maude Giroud, Pamina Gräsle, Sebastian Brings, Julia Szendrödi, Mauricio Berriel Diaz , Oliver Plettenburg, Stephan Herzig, Maria Rohm
Published in: Molecular Therapy, 2023, ISSN 1525-0024
Publisher: Cell Press
DOI: 10.1016/j.ymthe.2023.06.020

Virtual reality-empowered deep-learning analysis of brain cells

Author(s): Doris Kaltenecker, Rami Al-Maskari, Moritz Negwer, Luciano Hoeher, Florian Kofler, Shan Zhao, Mihail Todorov, Zhouyi Rong, Johannes Christian Paetzold, Benedikt Wiestler, Marie Piraud, Daniel Rueckert, Julia Geppert, Pauline Morigny, Maria Rohm, Bjoern H. Menze, Stephan Herzig, Mauricio Berriel Diaz & Ali Ertürk
Published in: Nature Methods, 2024, ISSN 1548-7105
Publisher: Nature group
DOI: 10.1038/s41592-024-02245-2

Endothelial Notch1 signaling in white adipose tissue promotes cancer cachexia

Author(s): Jacqueline Taylor, Leonie Uhl, Iris Moll, Sana Safatul Hasan, Lena Wiedmann, Jakob Morgenstern, Benedetto Daniele Giaimo, Tobias Friedrich, Elisenda Alsina-Sanchis , Francesca De Angelis Rigotti, Ronja Mülfarth, Sarah Kaltenbach, Darius Schenk, Felix Nickel, Thomas Fleming, David Sprinzak, Carolin Mogler, Thomas Korff, Adrian T Billeter, Beat P Müller-Stich, Mauricio Berriel Diaz, Tilman Borggre
Published in: Nature Cancer, 2023, ISSN 2662-1347
Publisher: Nature group
DOI: 10.1038/s43018-023-00622-y

Cancer cachexia: biomarkers and the influence of age

Author(s): Julia Geppert, MAria Rohm
Published in: Molecular Oncology, 2024, ISSN 1878-0261
Publisher: Wiley
DOI: 10.1002/1878-0261.13590

Diabetes increases mortality in patients with pancreatic and colorectal cancer by promoting cachexia and its associated inflammatory status

Author(s): Alexandra Chovsepian; Olga Prokopchuk; Gabriela Petrova; Tefta Gjini; Hanna Kuzi; Simone Heisz; Klaus-Peter Janssen; Marc E. Martignoni; Helmut Friess; Hans Hauner; Maria Rohm
Published in: Molecular Metabolism, 2023, ISSN 2212-8778
Publisher: Elsevier GmbH
DOI: 10.1016/j.molmet.2023.101729

Obesity and cancer—extracellular matrix, angiogenesis, and adrenergic signaling as unusual suspects linking the two diseases

Author(s): Natalia S. Pellegata; Mauricio Berriel Diaz; Maria Rohm; Stephan Herzig
Published in: Cancer and Metastasis Reviews, 2022, ISSN 0167-7659
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10555-022-10058-y

Aging Aggravates Cachexia in Tumor-Bearing Mice

Author(s): Geppert J, Walth AA, Terrón Expósito R, Kaltenecker D, Morigny P, Machado J, Becker M, Simoes E, Lima JDCC, Daniel C, Berriel Diaz M, Herzig S, Seelaender M, Rohm M
Published in: Cancers, 2021, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14010090

AMPK as a mediator of tissue preservation: time for a shift in dogma?

Author(s): Henning Tim Langer, Maria Rohm, Marcus DaSilva Goncalves & Lykke Sylow
Published in: Nature Reviews Endocrinology, Issue 2024 May 17, 2024, ISSN 1759-5037
Publisher: Nature group
DOI: 10.1038/s41574-024-00992-y

Non-peer reviewed articles (1)

Editorial: Ion channels and transporters in diabetes and metabolic diseases

Author(s): Michael Puljung, Elizabeth Haythorne, Maria Rohm, Natascia Vedovato
Published in: Frontiers in Pharmacology, 2022, ISSN 1663-9812
Publisher: Frontiers Media S.A.
DOI: 10.3389/fphar.2022.975812