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Top down regulation of motivated behaviors by lateral septal integration of cortico-hippocampal inputs

Project description

Brain regulation of motivated behaviours

The cognitive functions of the prefrontal cortex (PFC) and hippocampus are well studied, but their ability to regulate motivated behaviours, such as sociability, aggression, mating, or feeding, is much less understood. The lateral septum (LS) that receives inputs from the PFC and hippocampus and projects to the hypothalamus is ideally positioned to integrate cognitive information to regulate motivated behaviours. LS also receives numerous subcortical neuromodulatory inputs such as vasopressin, dopamine and serotonin. The EU-funded MotivatedBehaviors project aims to determine how the LS integrates cortical and neuromodulatory inputs to regulate motivated behaviours. The overarching goal of the project is to uncover changes occurring in disorders associated with social behavioural deficits, providing new therapeutic targets for disease treatment.

Call for proposal

ERC-2020-STG
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Host institution

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Address
Calle Serrano 117
28006 Madrid
Spain
Activity type
Research Organisations
EU contribution
€ 1 735 375

Beneficiaries (1)

AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 1 735 375
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations