Highly Informative Drug Screening by Overcoming NMR Restrictions

Información del proyecto

HiSCORE

Identificador del acuerdo de subvención: 951459

DOI 10.3030/951459

Fecha de la firma de la CE 8 Abril 2021

Fecha de inicio 1 Mayo 2021

Fecha de finalización 30 Abril 2027

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 13 992 719,00

Aportación de la UE € 13 992 719,00

Coordinado por

ECOLE NORMALE SUPERIEURE
France

Publicaciones

Peer reviewed articles (11)

Drug Screening of Achiral Molecules by Long-Lived States in NMR

Autores: A. Sonnefeld, A. Razanahoera, P. Pelupessy, G. Bodenhausen, and K. Sheberstov
Publicado en: Science Advances, 2022, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.ade2113

Selective Peptide Binders to the Perfluorinated Sulfonic Acid Ionomer Nafion

Autores: Dimitry Schmidt, Patrizia Gartner, Ivan Berezkin, Jens Rudat, Maximilian Bilger, Tom Grünert, Nadine Zimmerer, Philipp Quarz, Philip Scharfer, Julian Brückel, André P. Jung, Pooja Singh, Pooja Pooja, Benno Meier, Mareen Stahlberger, Wilhelm Schabel, Stefan Bräse, Gisela Lanza, and Alexander Nesterov-Mueller
Publicado en: Advanced Functional Materials, 2023, ISSN 1616-301X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202214932

Radical-Induced Low-Field 1H Relaxation in Solid Pyruvic Acid Doped with Trityl-OX063

Autores: M. Jurkutat, H. Kouřilová, D. Peat, K. Kouřil, A. S. Khan, A. J. Horsewill, J. F. MacDonald, J. Owers-Bradley, and B. Meier
Publicado en: The Journal of Physical Chemistry Letters, 2022, ISSN 1948-7185
Editor: American Chemical Society
DOI: 10.1021/acs.jpclett.2c02357

Deep regression with ensembles enables fast, first-order shimming in low-field NMR

Autores: Moritz Becker, Mazin Jouda, Anastasiya Kolchinskaya, and Jan Korvink
Publicado en: J. Magn. Reson, 2022, ISSN 1090-7807
Editor: Academic Press
DOI: 10.1016/j.jmr.2022.107151

Polychromatic Excitation of Delocalized Long-Lived Proton Spin States in Aliphatic Chains

Autores: A. Sonnefeld, G. Bodenhausen, and K. Sheberstov
Publicado en: Phys. Rev. Letters, Edición 129, 2022, ISSN 0031-9007
Editor: American Physical Society
DOI: 10.1103/physrevlett.129.183203

Radical-induced hetero-nuclear mixing and low-field 13C relaxation in solid pyruvic acid

Autores: H. Kouřilová, M. Jurkutat, D. Peat, K. Kouřil, A. S. Khan, A. J. Horsewill, J. F. MacDonald, J. Owers-Bradley, and B. Meier
Publicado en: Physical Chemistry Chemical Physics, 2022, ISSN 1463-9084
Editor: Royal society of chemistry
DOI: 10.1039/d2cp04535d

Sample-centred shimming enables independent parallel NMR detection

Autores: Yen-Tse Cheng, Mazin Youda, and Jan Korvink
Publicado en: Scientific Reports, 2022, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-022-17694-y

A cryogen-free, semi-automated apparatus for bullet-dynamic nuclear polarization with improved resolution

Autores: K. Kouřil, M. Gramberg, M. Jurkutat, H. Kouřilová, and B. Meier
Publicado en: Magnetic Resonance, 2021, ISSN 2699-0016
Editor: Göttingen: Copernicus Publications
DOI: 10.5194/mr-2-815-2021

Lenz Lenses in a Cryoprobe: Boosting NMR Sensitivity Toward Environmental Monitoring of Mass-Limited Samples

Autores: Monica Bastawrous, Rajshree Ghosh Biswas, Ronald Soong, Mazin Jouda, Neil MacKinnon, Dario Mage, Jan G. Korvink, and Andre J. Simpson
Publicado en: Anal. Chem, 2023, ISSN 0003-2700
Editor: American Chemical Society
DOI: 10.1021/acs.analchem.2c04203

Acquisitions with random shim values enhance AI-driven NMR shimming

Autores: Moritz Becker, Sören Lehmkuhl, Stefan Kesselheim, Jan G. Korvink, andMazin Jouda
Publicado en: J. Magn. Reson, 2022, ISSN 1090-7807
Editor: Academic Press
DOI: 10.1016/j.jmr.2022.107323

Paramagnetic Relaxivity of Delocalised Long-Lived States of Protons in Chains of CH2 Groups

Autores: A. Razanahoera, A. Sonnefeld, G. Bodenhausen, and K. Sheberstov
Publicado en: Magnetic Resonance, 2023, ISSN 2699-0016
Editor: Göttingen: Copernicus Publications
DOI: 10.5194/mr-4-47-2023