Project description
New generation of light microscopy with high depth and imaging resolution
The depth and imaging resolution of light microscopy are limited by the low specifications of light detectors. The goal of the EU-funded Brainiaqs project is to introduce quantum sensing technology for live tissue imaging by developing arrays of quantum sensors, based on superconducting single-photon detectors in a multi-photon microscope, to enhance imaging depth and resolution. A light-sensing technology idea was previously presented by the project partners and consists of multipixel superconducting nanowires, combining high efficiency with low noise and high time resolution. The current project will develop state-of-the-art technology, including cryogenic cooling systems, amplification and nanofabrication to build and operate an array of quantum sensors for integration in a multi-photon microscope, aiming at doubling the imaging depth and resolution.
Objective
The goal of this project is to deploy quantum sensing technology in life sciences applications by developing and implementing arrays of quantum sensors, based on superconducting single-photon detectors, in a multi-photon microscope to greatly enhance imaging depth and resolution in live tissues. Currently the depth and imaging resolution in light microscopy is limited because of the low specifications of light detectors. A proof-of-concept light sensing technology, developed in a previous FET-OPEN project can overcome this limitation. This technology consists of multipixel superconducting nanowires that have shown to be extremely sensitive, combining high efficiency with low noise and high time resolution. However, in order to deploy these detectors in multi-photon microscopy, the active area of the sensor needs to enlarged with an order of magnitude. In this project Brainiaqs we will develop state-of-the-art technology, including cryogenic cooling systems, (cryogenic) amplification and nanofabrication to build and operate an Array of Quantum sensors. In addition the new device will be integrated in a multi-photon microscope and deployed in an experiment, aiming at doubling the imaging depth and resolution, with respect to current technique. This will be a huge breakthrough for biological imaging experiments.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences optics microscopy
- natural sciences physical sciences electromagnetism and electronics superconductivity
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.2. - EXCELLENT SCIENCE - Future and Emerging Technologies (FET)
MAIN PROGRAMME
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H2020-EU.1.2.2. - FET Proactive
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
RIA - Research and Innovation action
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-FETPROACT-2019-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
2628 ER DELFT
Netherlands
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.