Networking Activities for Nanotechnology-Facilitated Cancer Theranostics

Informations projet

NANOFACTS

N° de convention de subvention: 952259

DOI

10.3030/952259

Projet clôturé

Date de signature de la CE 11 Juin 2020

Date de début 1 Janvier 2021

Date de fin 30 Juin 2024

Financé au titre de

• Twinning of research institutions

Coût total

€ 899 823,75

Contribution de l’UE

€ 899 823,75

Coordonné par

BIOSENSE INSTITUTE - RESEARCH AND DEVELOPMENT INSTITUTE FOR INFORMATION TECHNOLOGIES IN BIOSYSTEMS
Serbia

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (13)

Report on TSLs and WSLs in Cancer Theranostic Nanomaterials

Includes the main topics list of lecturers environment hosting institutions and responsible researchers list of instruments and models in use duration technical requirements and starting dates

Scientific Dissemination II

This deliverable will include all dissemination activities through publications in scientific journals and conferences in the months 19-36

NANOFACTS dissemination tools and material II

This report will summarise the communication materials produced during NANOFACTS, including online material, flyers, brochures, leaflets, posters, etc. from months 16 to 35

Report on TSLs and WSLs in Biosensing Diagnostics

Includes the main topics list of lecturers environment hosting institutions and responsible researchers list of instruments and models in use duration technical requirements and starting dates

Scientific Dissemination I

This deliverable will include all dissemination activities through publications in scientific journals and conferences up to the month 18

Delivered trainings on research management and administration skills in the first year

A detailed overview on delivered trainings presented topics participants and outcomes

PEDR - Plan for the Exploitation and Dissemination of Results

The PEDR will be developed at an early stage outlining among others the dissemination strategy the key communication messages and content to be used by NANOFACTS as well as to identify and employ the most suitable channels

Report on participation of BIOS-researchers at conferences/events

Summarises all the conferences/events and outcomes of knowledge transfer to BIOS researchers

Evolution of the publications in high impact journals in the relevant research fields

Introducing the Continuous reporting tool which measures the evolution compared to a reference period of three years prior to the signature of the grant agreement in of the peerreviewed publications in high impact journals in the top 10 impact ranked journals in the reseaarch area related to nanomaterials for cancer therapy and diagnostics

Delivered trainings on research management and administration skills in the second year

A detailed overview on delivered trainings, presented topics, participants and outcomes

Delivered trainings on research management and administration skills in the third year

A detailed overview on delivered trainings, presented topics, participants and outcomes

NANOFACT Web-portal, and Social Media Groups

Web and Social Media Groups will present a knowledge repository and communicator to promote project activities and results

NANOFACTS dissemination tools and material I

This report will summarise the communication materials produced during NANOFACTS including online material flyers brochures leaflets posters etc up to the month 15

Open Research Data Pilot (2)

Data Management Plan (DMP)

Outlines the framework for all the issues related to data management

Data Management Plan (DMP) v2

Updates the framework for all the issues related to data management

Publications

Conference proceedings (13)

Functionalized Mesoporous Silica Nanoparticles for Drug Delivery to Glioblastoma, Multiforme

Auteurs: N. Ž. Knežević, N. Ilić, G. N. Kaluđerović
Publié dans: 22nd IEEE International Conference on Nanotechnology (IEEE-NANO 2022), 2022, ISBN 978-1-6654-5225-0
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.1109/nano54668.2022.9928669

Cyclodextrin-Capped Mesoporous Silica-Based Nanomaterials for pH-Responsive Targeted Theranostics of Glioblastoma Multiforme

Auteurs: Nikola Knežević; Minja Mladenović; Mirjana Mundžić; Aleksandra Pavlović; Mila Djisalov; Teodora Knežić; Ivana Gadjanski
Publié dans: International meet on pharmaceutics and drug delivery systems (PHARMAMEET2023), Numéro 7, 2023
Éditeur: Albedo
DOI: 10.5281/zenodo.7665435

Investigation of the surface interactions of indole with mesoporous silica using FTIR spectroscopy and hyperspectral imaging

Auteurs: Aleksandra Pavlović; Nikola Radnović; Marko Panić; Nikola Knežević; Branislav Jović
Publié dans: 58. Counseling of the Serbian Chemical Society, Numéro 1, 2022
Éditeur: Serbian Chemical Society
DOI: 10.5281/zenodo.6670041

pH- and Redox-Responsive Cancer Nanotheranostics Based on Cyclodextrin-Capped Mesoporous Silica

Auteurs: Nikola Knežević; Mirjana Mundžić; Minja Mladenović; Aleksandra Pavlović; Amelia Ultimo; Oliviero Gobbo; Eduardo Ruiz-Hernandez; Maria Santos-Martinez
Publié dans: 20th International Conference on Nanosciences & Nanotechnologies, Numéro 1, 2023
Éditeur: Aristotle University of Thessaloniki, Greece
DOI: 10.5281/zenodo.8158522

Novel cost-effective electrochemical systems for sensing cancer biomarkers

Auteurs: Knežević, N., Jarić, S., Kundačina, I., Radonić, V., Bobrinetskiy, I.
Publié dans: 8th International Conference on Bio-Sensing Technology, 2024
Éditeur: Elsevier
DOI: 10.5281/zenodo.12626248

Low-cost platform for determination of NTproBNP in saliva using graphene-based aptasensor

Auteurs: Jarić, S., Bobrinetrskiy I.
Publié dans: 8th International Conference on Bio-Sensing Technology,, 2024
Éditeur: Elsevier
DOI: 10.5281/zenodo.12624103

Potential of MRI-based sensing of cargo release from mesoporous silica for tracking drug delivery capabilities

Auteurs: Knežević, N.Ž., Mundžić, M., Lazović, J., Ultimo, A., Mladenović, M., Pavlović, A., Gobbo, O.L., Ruiz-Hernandez, E., Santos-Martinez. M.J.
Publié dans: Nanospain 2024, 2024
Éditeur: Phantoms foundation
DOI: 10.5281/zenodo.11516624

LAMP PRIMER DESIGN FOR MONITORING GENE EXPRESSION OF TUMOR MARKERS IN 3D CANCER CULTURES

Auteurs: Teodora Knežić; Mila Djisalov
Publié dans: 15th Scientific Conference Students encountering science – StES 2022, 2022
Éditeur: University of Banja Luka
DOI: 10.5281/zenodo.7400865

potential of mesoporous silica nanoparticles for applications in targeted treatmernt of cance

Auteurs: Minja Mladenovic, Mirjana Mundzic, Aleksandra Pavlovic, Nikola Knezevic
Publié dans: 5th Congress of the “Serbian Association for Cancer Research – SDIR, 2021
Éditeur: Serbian Association for Cancer Research
DOI: 10.5281/zenodo.5769293

Electrochemical Detection of MMP-2 Using Graphene-Based Aptasensor

Auteurs: Stefan Jarić, Silvia Schobesberger, Peter Ertl, Nikola Ž Knežević, Ivan Bobrinetskiy
Publié dans: Proceedings, 2024, ISSN 2504-3900
Éditeur: MDPI
DOI: 10.3390/proceedings2024097057

Nanosensor for Glutathione

Auteurs: Pavlović, Aleksandra; Mladenović, Minja; Mundžić, Mirjana
Publié dans: Students encountering science – StES 2022, Numéro 1, 2022
Éditeur: University of Banja Luka
DOI: 10.5281/zenodo.7400808

Anticancer Applications of Mesoporous Silica Nanoparticles

Auteurs: Minja Mladenović; Mirjana Mundžić; Aleksandra Pavlović; Nikola Knežević
Publié dans: 7th NANO TODAY conference, Numéro 1, 2021
Éditeur: NANO TODAY
DOI: 10.5281/zenodo.5733889

Stimuli-Responsive Mesoporous Silica Nanoparticles for Applications in Cancer Theranostics

Auteurs: Nikola Knezevic, Minja Mladenovic, Mirjana Mundzic and Aleksandra Pavlovic
Publié dans: 2021 MRS Fall Meeting, 2021
Éditeur: Materials Research Society
DOI: 10.5281/zenodo.6200633

Peer reviewed articles (19)

Amino-acid functionalized porous silicon nanoparticles for the delivery of pDNA.

Auteurs: Chaix, Arnaud; Cueto-Diaz, Eduardo; Delalande, Anthony; Knezevic, Nikola; Midoux, Patrick; Durand, Jean-Olivier; Pichon, Chantal; Cunin, Frédérique
Publié dans: RSC Advances, Numéro 9, 2019, Page(s) 31895-31899, ISSN 2046-2069
Éditeur: Royal Society of Chemistry
DOI: 10.1039/c9ra05461h

Sensor-integrated brain-on-a-chip platforms: Improving the predictive validity in neurodegenerative research

Auteurs: Sarah Spitz, Silvia Schobesberger, Konstanze Brandauer, Peter Ertl
Publié dans: Bioengineering and Translational Medicine, 2023, ISSN 2380-6761
Éditeur: Wiley
DOI: 10.1002/btm2.10604

Direct electrochemical reduction of graphene oxide thin film for aptamer-based selective and highly sensitive detection of Matrix metalloproteinase 2

Auteurs: Jaric, Stefan; Schobesberger, Silvia; Ertl, Peter; Bobrinetskiy, Ivan; Knezevic, Nikola Z.
Publié dans: Talanta, Numéro 9, 2024, Page(s) 126079, ISSN 0039-9140
Éditeur: Elsevier BV
DOI: 10.1016/j.talanta.2024.126079

Nanocomposite formulation for a sustained release of free drug and drug-loaded responsive nanoparticles: an approach for a local therapy of glioblastoma multiforme

Auteurs: Luiza C. S. Erthal, Yang Shi, Kieron J. Sweeney, Oliviero L. Gobbo & Eduardo Ruiz-Hernandez
Publié dans: Scientific Reports, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-32257-5

Intranasal Polymeric and Lipid-Based Nanocarriers for CNS Drug Delivery

Auteurs: Rebecca Maher, Almudena Moreno-Borrallo, Dhruvi Jindal, Binh T. Mai, Eduardo Ruiz-Hernandez, Andrew Harkin
Publié dans: Pharmaceutics, 2023, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15030746

Advanced mesoporous silica nanocarriers in cancer theranostics and gene editing applications

Auteurs: Kristina Živojević, Minja Mladenović, Mila Djisalov, Mirjana Mundzic, Eduardo Ruiz-Hernandez, Ivana Gadjanski, Nikola Ž. Knežević
Publié dans: Journal of Controlled Release, Numéro 337, 2021, Page(s) 193-211, ISSN 0168-3659
Éditeur: Elsevier BV
DOI: 10.1016/j.jconrel.2021.07.029

Chlorotoxin-functionalized mesoporous silica nanoparticles for pH-responsive paclitaxel delivery to Glioblastoma multiforme

Auteurs: Mirjana Mundžić, Amelia Ultimo, Minja Mladenović, Aleksandra Pavlović, Oliviero L. Gobbo, Eduardo Ruiz-Hernandez, Maria Jose Santos-Martinez, Nikola Ž. Knežević
Publié dans: Heliyon, Numéro 11, 2025, Page(s) e41151, ISSN 2405-8440
Éditeur: Cell Press
DOI: 10.1016/j.heliyon.2024.e41151

pH-Responsive Release of Ruthenium Metallotherapeutics from Mesoporous Silica-Based Nanocarriers

Auteurs: Minja Mladenović, Ibrahim Morgan, Nebojša Ilić, Mohamad Saoud, Marija V. Pergal, Goran N. Kaluđerović, Nikola Ž. Knežević
Publié dans: Pharmaceutics, Numéro 13/4, 2021, Page(s) 460, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13040460

Advances in Non-Animal Testing Approaches towards Accelerated Clinical Translation of Novel Nanotheranostic Therapeutics for Central Nervous System Disorders

Auteurs: Lynch, M. J., Gobbo, O. L.
Publié dans: Nanomaterials, 2021, ISSN 2079-4991
Éditeur: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/nano11102632

High-Capacity Mesoporous Silica Nanocarriers of siRNA for Applications in Retinal Delivery

Auteurs: Amelia Ultimo, Mar Orzaez, Maria J. Santos-Martinez, Ramón Martínez-Máñez, María D. Marcos, Félix Sancenón, Eduardo Ruiz-Hernández
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1661-6596
Éditeur: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/ijms24032753

Biosensors for Cancer Biomarkers Based on Mesoporous Silica Nanoparticles

Auteurs: Mladenović, M., Jarić, S., Mundžić, M., Pavlović, A., Bobrinetskiy, I., Knežević, N.Ž
Publié dans: Biosensors, Numéro 14(7), 2024, Page(s) 326, ISSN 2079-6374
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios14070326

In Situ-Forming Gels Loaded with Stimuli-Responsive Gated Mesoporous Silica Nanoparticles for Local Sustained Drug Delivery

Auteurs: Cristina de la Torre, Carmen Coll, Amelia Ultimo, Félix Sancenón, Ramón Martínez-Máñez. Eduardo Ruiz-Hernández
Publié dans: Pharmaceutics, 2023, ISSN 1999-4923
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics15041071

Comparative Study of Field-Effect Transistors Based on Graphene Oxide and CVD Graphene in Highly Sensitive NT-proBNP Aptasensors

Auteurs: Kudriavtseva, Anastasiia; Jarić, Stefan; Nekrasov, Nikita; Orlov, Alexey V.; Gadjanski, Ivana; Bobrinetskiy, Ivan; Nikitin, Petr I.; Knežević, Nikola
Publié dans: Biosensors, Numéro 14, 2024, ISSN 2079-6374
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios14050215

Magnetic nanoarchitectures for cancer sensing, imaging and therapy

Auteurs: Nikola Ž. Knežević; Ivana Gadjanski; Ivana Gadjanski; Jean-Olivier Durand
Publié dans: Journal of materials chemistry‎ B, Numéro 7, 2019, Page(s) 9-23, ISSN 2050-7518
Éditeur: Royal Society of Chemistry
DOI: 10.1039/c8tb02741b

MRI-based sensing of pH-responsive content release from mesoporous silica nanoparticles

Auteurs: Mirjana Mundžić, Jelena Lazović, Minja Mladenović, Aleksandra Pavlović, Amelia Ultimo, Oliviero L. Gobbo, Eduardo Ruiz-Hernandez, Maria Jose Santos-Martinez, Nikola Ž. Knežević
Publié dans: Journal of Sol-Gel Science and Technology, 2024, ISSN 0928-0707
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10971-024-06422-9

Mesoporous Silica Nanoparticles for pH-Responsive Delivery of Iridium Metallotherapeutics and Treatment of Glioblastoma Multiforme

Auteurs: Knežević, N.Ž.; Ilić, N.; Kaluđerović, G.N.
Publié dans: Inorganics, 2022, ISSN 2304-6740
Éditeur: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/inorganics10120250

Functionalized Periodic Mesoporous Organosilica Nanoparticles for Loading and Delivery of Suramin

Auteurs: Knežević; Djordjević; Kojić; Janaćković
Publié dans: Inorganics, Numéro 7, 2019, Page(s) 16, ISSN 2304-6740
Éditeur: MDPI
DOI: 10.3390/inorganics7020016

One-Step Photochemical Immobilization of Aptamer on Graphene for Label-Free Detection of NT-proBNP

Auteurs: Nekrasov, N.; Kudriavtseva, A.; Orlov, A.V.; Gadjanski, I.; Nikitin, P.I.; Bobrinetskiy, I.; Knežević, N.Ž.
Publié dans: Biosensors, 2022, ISSN 2079-6374
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios12121071

A versatile gold leaf immunosensor with a novel surface functionalization strategy based on protein L and trastuzumab for HER2 detection

Auteurs: Ivana Kundacina, Silvia Schobesberger, Stefan Kittler, Helena Thumfart, Oliver Spadiut, Peter Ertl, Nikola Ž. Knežević, Vasa Radonic
Publié dans: Scientific Reports, Numéro 15, 2025, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-024-83961-9

Other (2)

pH-responsive Nanosystems for Targeted Drug Delivery to Glioblastoma Multiforme and MRI-facilitated Monitoring of Content Release

Auteurs: Mundžić, M., Ultimo, A., Lazović, J., Mladenović M, Pavlović A, Gobbo O, Ruiz-Hernandez E, Santos-Martinez MJ, Knežević N.Ž.
Publié dans: PREPRINT, 2023
Éditeur: Researchsquare
DOI: 10.21203/rs.3.rs-3709910/v1

A Versatile Gold Leaf Immunosensor with a Novel Functionalization Strategy Based on Protein L-Modified Surface for Efficient Her2 Detection

Auteurs: Kundacina, I., Schobesberger, S. Kittler, S., Thumfart, H., Spadiut, O., Ertl, P, Knezevic, N.Ž. Radonic, V.
Publié dans: PREPRINT, 2024
Éditeur: SSRN-Elsevier
DOI: 10.2139/ssrn.4740306