Pioneering Strategies Against Bacterial Infections

Informations projet

PEST-BIN

N° de convention de subvention: 955626

DOI

10.3030/955626

Projet clôturé

Date de signature de la CE 28 Août 2020

Date de début 1 Janvier 2021

Date de fin 31 Decembre 2024

Financé au titre de

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coût total

€ 4 144 986,00

Contribution de l’UE

€ 4 144 986,00

Coordonné par

DANMARKS TEKNISKE UNIVERSITET
Denmark

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (21)

Diagnostic biomarkers obtained by MS proteomics
MS proteomics analytical pipeline for analysing bacterial infection systems
Graphene-polymer composites with enhanced antibacterial properties, suitable for mass production
Outreach activities accomplished by each ESR
Consolidated list of targets for drug development based on computational analysis
Vacancies advertised
Consolidated list of diagnostic markers based on omics data integration
Functionalized graphene diagnostic chip
Summer School 3 (M33)

Summer School 3

Summer School 2 (M21)

Summer Schools 2 M21

MS proteomics-based targets for drug development
Exploitation of results
Magnetic nanoparticles axially coated with graphene, functionalized with antibiotics
Conferences (M12)

Conferences M12

ESR scientific publications
PhD degrees delivered

PhD degrees delivered. CUT and UGOT ESRs will continue for another year before obtaining their doctoral degrees (local doctoral school rules). PhD degrees in Sweden lasts for minimum 4 years. The last year will be co-financed by CUT and UGOT.

Recruitment workshop
Conferences (M36)
PTM conferences attended by ESRs
Website & associated platforms operational

Website associated platforms operational

New antibiotics discovered by library screening

Publications

Peer reviewed articles (23)

Recent Developments in the Ruthenium‐Catalyzed Azide Alkyne Cycloaddition (RuAAC) Reaction

Auteurs: Flavia Ferrara, Tamás Beke‐Somfai, Nina Kann
Publié dans: European Journal of Organic Chemistry, Numéro 27, 2024, ISSN 1434-193X
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/ejoc.202400113

Recent progress in quantitative phosphoproteomics

Auteurs: Katharina Zittlau, Payal Nashier, Claudia Cavarischia-Rega, Boris Macek, Philipp Spät, Nicolas Nalpas
Publié dans: Expert Review of Proteomics, Numéro 20, 2024, Page(s) 469-482, ISSN 1478-9450
Éditeur: Future Drugs Ltd.
DOI: 10.1080/14789450.2023.2295872

High Mobility Graphene on EVA/PET

Auteurs: Munis Khan, Kornelia Indykiewicz, Pui Lam Tam and August Yurgens
Publié dans: Nanomaterials, Numéro 20794991, 2021, ISSN 2079-4991
Éditeur: MDPI
DOI: 10.3390/nano12030331

Phosphoproteome Dynamics of Streptomyces rimosus during Submerged Growth and Antibiotic Production

Auteurs: Ela Šarić, Gerry A. Quinn, Nicolas Nalpas, Tina Paradžik, Saša Kazazić, Želimira Filić, Maja Šemanjski, Paul Herron, Iain Hunter, Boris Maček, Dušica Vujaklija
Publié dans: mSystems, Numéro 7, 2023, ISSN 2379-5077
Éditeur: mSystems
DOI: 10.1128/msystems.00199-22

Orientation of graphene nanosheets in magnetic fields

Auteurs: Viney Ghai, Sajjad Pashazadeh, Hengzhi Ruan, Roland Kádár
Publié dans: Progress in Materials Science, Numéro 143, 2024, Page(s) 101251, ISSN 0079-6425
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.pmatsci.2024.101251

Polysaccharide-based antibacterial coating technologies

Auteurs: Hengzhi Ruan, Alexandra Aulova, Viney Ghai, Santosh Pandit, Martin Lovmar, Ivan Mijakovic, Roland Kádár
Publié dans: Acta Biomaterialia, Numéro 168, 2024, Page(s) 42-77, ISSN 1742-7061
Éditeur: Elsevier BV
DOI: 10.1016/j.actbio.2023.07.023

BacSPaD: A Robust Bacterial Strains’ Pathogenicity Resource Based on Integrated and Curated Genomic Metadata

Auteurs: Sara Ribeiro, Guillaume Chaumet, Karine Alves, Julien Nourikyan, Lei Shi, Jean-Pierre Lavergne, Ivan Mijakovic, Simon de Bernard, Laurent Buffat
Publié dans: Pathogens, Numéro 13, 2024, Page(s) 672, ISSN 2076-0817
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pathogens13080672

Graphene Oxide Attenuates Toxicity of Amyloid‐β Aggregates in Yeast by Promoting Disassembly and Boosting Cellular Stress Response

Auteurs: Xin Chen, Santosh Pandit, Lei Shi, Vaishnavi Ravikumar, Julie Bonne Køhler, Ema Svetlicic, Zhejian Cao, Abhroop Garg, Dina Petranovic, Ivan Mijakovic
Publié dans: Advanced Functional Materials, Numéro 33, 2024, ISSN 1616-301X
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202304053

Proteome Dynamics during Antibiotic Persistence and Resuscitation

Auteurs: Maja Semanjski, Fabio Lino Gratani, Till Englert, Payal Nashier, Viktor Beke, Nicolas Nalpas, Elsa Germain, Shilpa George, Christiane Wolz, Kenn Gerdes, Boris Macek
Publié dans: American Societu for Microbiology, Numéro 23795077, 2021, ISSN 2379-5077
Éditeur: Amer Soc Microbiology
DOI: 10.1128/msystems.00549-21

The Molecules Gateway: A Homogeneous, Searchable Database of 150k Annotated Molecules from Actinomycetes

Auteurs: Matteo Simone, Marianna Iorio, Paolo Monciardini, Massimo Santini, Niccolò Cantù, Arianna Tocchetti, Stefania Serina, Cristina Brunati, Thomas Vernay, Andrea Gentile, Mattia Aracne, Marco Cozzi, Justin J. J. van der Hooft, Margherita Sosio, Stefano Donadio, Sonia I. Maffioli
Publié dans: Journal of Natural Products, Numéro 87, 2024, Page(s) 2615-2628, ISSN 0163-3864
Éditeur: American Chemical Society
DOI: 10.1021/acs.jnatprod.4c00857

Molecular dissection of the chromosome partitioning protein RocS and regulation by phosphorylation

Auteurs: Margaux Demuysere, Adrien Ducret, Christophe Grangeasse
Publié dans: Journal of Bacteriology, Numéro 206, 2024, ISSN 0021-9193
Éditeur: American Society for Microbiology
DOI: 10.1128/jb.00291-24

Bad to the bone? – Genomic analysis of Enterococcus isolates from diverse environments reveals that most are safe and display potential as food fermentation microorganisms

Auteurs: Belay Tilahun Tadesse, Ema Svetlicic, Shuangqing Zhao, Nega Berhane, Carsten Jers, Christian Solem, Ivan Mijakovic
Publié dans: Microbiological Research, Numéro 283, 2024, Page(s) 127702, ISSN 0944-5013
Éditeur: Elsevier BV
DOI: 10.1016/j.micres.2024.127702

Pleomorphic Variants of Borreliella (syn. Borrelia) burgdorferi Express Evolutionary Distinct Transcriptomes

Auteurs: Nina Čorak, Sirli Anniko, Christina Daschkin-Steinborn, Viktoria Krey, Sara Koska, Momir Futo, Tin Široki, Innokenty Woichansky, Luka Opašić, Domagoj Kifer, Anja Tušar, Horst-Günter Maxeiner, Mirjana Domazet-Lošo, Carsten Nicolaus, Tomislav Domazet-Lošo
Publié dans: International Journal of Molecular Sciences, Numéro 24, 2025, Page(s) 5594, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24065594

High mobility graphene field effect transistors on flexible EVA/PET foils

Auteurs: Munis Khan, Jie Ji, Binbin Zhou, Peter U Jepsen, Peter Boggild, August Yurgens
Publié dans: 2D Materials, Numéro 11, 2024, Page(s) 035022, ISSN 2053-1583
Éditeur: 2D Materials
DOI: 10.1088/2053-1583/ad4b36

A novel time-lapse imaging method for studying developing bacterial biofilms

Auteurs: Momir Futo; Tin Široki; Sara Koska; Nina Čorak; Anja Tušar; Mirjana Domazet-Lošo; Tomislav Domazet-Lošo
Publié dans: Crossref, Numéro 1, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-24431-y

Advanced Nanomaterials for Cancer Therapy: Gold, Silver, and Iron Oxide Nanoparticles in Oncological Applications

Auteurs: Priyanka Singh, Santosh Pandit, Sri Renukadevi Balusamy, Mukil Madhusudanan, Hina Singh, H. Mohamed Amsath Haseef, Ivan Mijakovic
Publié dans: Advanced Healthcare Materials, 2024, ISSN 2192-2640
Éditeur: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202403059

Graphene thermocouple fabricated on a flexible and transparent substrate

Auteurs: Youngwoo Nam, Daewon Gu, Munis Khan, August Yurgens
Publié dans: AIP Advances, Numéro 14, 2024, ISSN 2158-3226
Éditeur: American Institute of Physics Inc.
DOI: 10.1063/5.0203178

Genomic characterization and assessment of pathogenic potential of Legionella spp. isolates from environmental monitoring

Auteurs: Ema Svetlicic, Daniel Jaén-Luchoro, Roberta Sauerborn Klobucar, Carsten Jers, Snjezana Kazazic, Damjan Franjevic, Goran Klobucar, Brian G. Shelton and Ivan Mijakovic*
Publié dans: Frontiers in Microbiology, 2023, ISSN 1664-302X
Éditeur: Frontiers Media
DOI: 10.3389/fmicb.2022.1091964

Biomimetic Antibacterial Gelatin Hydrogels with Multifunctional Properties for Biomedical Applications

Auteurs: Hengzhi Ruan, Marko Bek, Santosh Pandit, Alexandra Aulova, Jian Zhang, Philip Bjellheim, Martin Lovmar, Ivan Mijakovic, Roland Kádár
Publié dans: ACS Applied Materials & Interfaces, Numéro 15, 2023, Page(s) 54249-54265, ISSN 1944-8244
Éditeur: American Chemical Society
DOI: 10.1021/acsami.3c10477

CHAMP delivers accurate taxonomic profiles of the prokaryotes, eukaryotes, and bacteriophages in the human microbiome

Auteurs: Sara Pita, Pernille Neve Myers, Joachim Johansen, Jakob Russel, Mads Cort Nielsen, Aron C. Eklund, Henrik Bjørn Nielsen
Publié dans: Frontiers in Microbiology, Numéro 15, 2024, ISSN 1664-302X
Éditeur: Frontiers Media
DOI: 10.3389/fmicb.2024.1425489

An integrated workflow for enhanced taxonomic and functional coverage of the mouse fecal metaproteome

Auteurs: Nicolas Nalpas, Lesley Hoyles, Viktoria Anselm, Tariq Ganief, Laura Martinez-GiliORCID Icon, Cristina Grau, Irina Droste-Borel, Laetitia Davidovic, Xavier Altafaj, Marc-Emmanuel Dumas & Boris Macek
Publié dans: Gut Microbes, Numéro 19490976, 2021, ISSN 1949-0976
Éditeur: Landes Bioscience
DOI: 10.1080/19490976.2021.1994836

Achieving Long‐Range Arbitrary Uniform Alignment of Nanostructures in Magnetic Fields

Auteurs: Viney Ghai, Santosh Pandit, Magnus Svensso, Ragnar Larsson, Aleksandar Matic, Roselle Ngaloy, Saroj P. Dash, Ann Terry, Kim Nygård, Ivan Mijakovic, Roland Kádár
Publié dans: Advanced Functional Materials, 2024, ISSN 1616-301X
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.202406875

3D printed inserts for reproducible high throughput screening of cell migration

Auteurs: Abhayraj S. Joshi, Mukil Madhusudanan, Ivan Mijakovic
Publié dans: Frontiers in Cell and Developmental Biology, Numéro 11, 2023, ISSN 2296-634X
Éditeur: Frontiers
DOI: 10.3389/fcell.2023.1256250

Other (2)

E. coli Toxin YjjJ (HipH) Is a Ser/Thr Protein Kinase That Impacts Cell Division, Carbon Metabolism, and Ribosome Assembly

Auteurs: Fabio Lino Gratani, Till Englert, Payal Nashier, Peter Sass, Laura Czech, Niels Neumann, Sofia Doello, Petra Mann, Rudolf Blobelt, Siegfried Alberti, Karl Forchhammer, Gert Bange , Katharina Höfer, Boris Macek
Publié dans: 2022
Éditeur: ASM Journals
DOI: 10.1128/msystems.01043-22

Identifying Novel Determinants of Bacterial Pathogenicity using Phylogenetic-based Orthology Analysis

Auteurs: RIBEIRO, Sara
Publié dans: Numéro 1, 2024
Éditeur: Zenodo
DOI: 10.5281/zenodo.13694408