Future Toxicology: Better predicting Toxicant-induced cell fate.

Project description

Improving the prediction of chemical toxicity

Modern toxicology is moving towards computational approaches where toxicity prediction is based on datasets of chemical structures and toxicological outcomes. However, our understanding of how chemicals affect cells remains incomplete, hampering the effectiveness of such approaches. The scope of the EU-funded TOXIFATE project is to develop new assays to detect chemical-induced changes in cells by focussing on myotoxicity, a severe toxicity characterised by skeletal muscle breakdown. Scientists will generate transcriptomic data describing cell stress and cell death responses and use them to develop novel computational approaches towards improved toxicity prediction.

Fields of science

• medical and health sciences › basic medicine › toxicology

Programme(s)

• H2020-EU.1.3.1. - Fostering new skills by means of excellent initial training of researchers

Topic(s)

• MSCA-ITN-2020 - Innovative Training Networks

Call for proposal

H2020-MSCA-ITN-2020
See other projects for this call

Funding Scheme

MSCA-ITN-EID - European Industrial Doctorates

Coordinator

NATIONAL UNIVERSITY OF IRELAND GALWAY

Address

University Road
H91 Galway
Ireland

Activity type

Higher or Secondary Education Establishments

Links

EU contribution

€ 274 684,32

Participants (1)

PROTOQSAR 2000 SL

Spain

EU contribution

€ 250 904,88

Address

C Salvador Ferrandis Luna 45 Pta 23
46018 Valencia

Activity type

Private for-profit entities (excluding Higher or Secondary Education Establishments)

Links