Opto-Biomechanical Eye Research Network

Project Information

OBERON

Grant agreement ID: 956720

DOI

10.3030/956720

Project closed

EC signature date 7 September 2020

Start date 1 January 2021

End date 28 February 2025

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 3 881 175,48

EU contribution

€ 3 881 175,48

Coordinated by

UNIVERSIDADE DO MINHO
Portugal

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (3)

Project website and social media accounts

Set up the project website and social media profiles LinkedIn Twitter Facebook and regularly post new content about the project

Outreach activities/ Scientific presentations by ESRs

This deliverable will be integrated by several items distributed between month 6 and month 42

Newsletters/ Press releases sent

This deliverable will be integrated by several items distributed between month 1 and month 48

Documents, reports (1)

Published ESR vacancies

Central advertisement of all ESR vacancies

Other (1)

Closing meeting organized

Report with the program and main conclusions of the final meeting

Publications

Peer reviewed articles (51)

Change in monochromatic aberrations with accommodation in a large adult population

Author(s): María Mechó-García, María Arcas-Carbonell, Elvira Orduna-Hospital, Ana Sánchez-Cano, Vicente Fernández-Sánchez, Rute J. Macedo-de-Araújo, Paulo Fernandes, José Manuel González-Méijome, Jos J. Rozema
Published in: BMC Ophthalmology, Issue 25, 2025, ISSN 1471-2415
Publisher: BioMed Central
DOI: 10.1186/s12886-025-03947-7

Anterior Chamber and Retinal Morphological Changes During Accommodation in Different Age Ranges

Author(s): María Arcas-Carbonell, Elvira Orduna-Hospital, Guisela Fernández-Espinosa, María Mechó-García, José Juan Castro-Torres, Ana Sánchez-Cano
Published in: Current Eye Research, Issue 49, 2024, Page(s) 671-681, ISSN 0271-3683
Publisher: Swets & Zeitlinger
DOI: 10.1080/02713683.2024.2320771

Refractive development I: Biometric changes during emmetropisation

Author(s): Jos Rozema
Published in: Ophthalmic Physiological Optics, 2023, ISSN 0275-5408
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/opo.13094

Effects of capsulorhexis size and position on post-surgical IOL alignment

Author(s): Liying Feng, Carmen Canovas Vidal, Henk Weeber, Bram Koopman, Shima Bahramizadeh Sajadi, Jos J. Rozema
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-82377-9

Refractive development II: Modelling normal and myopic eye growth

Author(s): Jos J. Rozema, Arezoo Farzanfar
Published in: Ophthalmic and Physiological Optics, Issue 45, 2024, Page(s) 120-134, ISSN 0275-5408
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/opo.13412

Evaluation of the mechanical stability of intraocular lenses using digital image correlation

Author(s): Iulen Cabeza-Gil, Javier Frechilla, Begoña Calvo
Published in: Scientific Reports, Issue 13, 2023, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-023-36694-0

Dynamic in vivo mapping of the gradient refractive index and strain distribution of the human lens under accommodative stress

Author(s): Sabine Kling, Vahoura Tahsini, Farhad Hafezi
Published in: Experimental Eye Research, Issue 255, 2025, Page(s) 110332, ISSN 0014-4835
Publisher: Academic Press
DOI: 10.1016/j.exer.2025.110332

The Effect of the Zonular Fiber Angle of Insertion on Accommodation

Author(s): Liying Feng, Barbara Pierscionek, Henk Weeber, Carmen Canovas Vidal, Jos J. Rozema
Published in: Vision, Issue 8, 2024, Page(s) 45, ISSN 2411-5150
Publisher: MDPI
DOI: 10.3390/vision8030045

A POD-NN methodology to determine in vivo mechanical properties of soft tissues. Application to human cornea deformed by Corvis ST test

Author(s): Elena Redaelli, Begoña Calvo, Jose Felix Rodriguez Matas, Giulia Luraghi, Jorge Grasa
Published in: Computers in Biology and Medicine, Issue 187, 2025, Page(s) 109792, ISSN 0010-4825
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2025.109792

Storage-induced mechanical changes of porcine lenses assessed with optical coherence elastography and inverse finite element modeling

Author(s): Vahoura Tahsini, Iulen Cabeza Gil, Sabine Kling
Published in: Frontiers in Bioengineering and Biotechnology, Issue 12, 2024, ISSN 2296-4185
Publisher: Frontiers Media SA
DOI: 10.3389/fbioe.2024.1398659

Establishing Standardization Guidelines For Finite-Element Optomechanical Simulations of Refractive Laser Surgeries: An Application to Photorefractive Keratectomy.

Author(s): Fantaci, Benedetta; Calvo, Begoña; Barraquer, Rafael; Picó, Andrés; Ariza-Gracia, Miguel Ángel
Published in: Translational vision science & technology, Issue 23, 2024, ISSN 2164-2591
Publisher: ARVO journals
DOI: 10.48350/196817

Non-contact tonometry: predicting intraocular pressure using a material—corneal thickness—independent methodology

Author(s): Elena Redaelli, Begoña Calvo, Jose Felix Rodriguez Matas, Giulia Luraghi, Jorge Grasa
Published in: Frontiers in Bioengineering and Biotechnology, Issue 12, 2024, ISSN 2296-4185
Publisher: Frontiers in Bioengineering and Biotechnology
DOI: 10.3389/fbioe.2024.1406870

Intracapsular accommodation mechanism in terms of lens curvature gradient

Author(s): Veronica Lockett‐Ruiz, Rafael Navarro, Norberto López‐Gil
Published in: Ophthalmic and Physiological Optics, Issue 44, 2024, Page(s) 334-346, ISSN 0275-5408
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/opo.13271

Impact of material property modifications on optical performance: a multidisciplinary study in the human eye under different intraocular pressures

Author(s): Saeed Zahabi, Milad Salimibani, Agnieszka Jóźwik, Magdalena Asejczyk
Published in: Biomedical Optics Express, Issue 16, 2025, Page(s) 2254, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.555315

The major influence of anterior and equatorial zonular fibres on the far-to-near accommodation revealed by a 3D pre-stressed model of the anterior eye

Author(s): Yutian Pu, Ziyuan Liu, Lin Ye, Yunxin Xia, Xiaoyong Chen, Kehao Wang, Barbara K. Pierscionek
Published in: Computer Methods and Programs in Biomedicine, Issue 242, 2024, Page(s) 107815, ISSN 0169-2607
Publisher: Elsevier BV
DOI: 10.1016/j.cmpb.2023.107815

Unraveling the impact of laser refractive surgery on corneal ectasia: an in silico study

Author(s): Benedetta Fantaci, José Félix Rodriguez Matas, Vittoria Squartecchia, Lucia Vavassori, Begoña Calvo
Published in: Frontiers in Bioengineering and Biotechnology, Issue 13, 2025, ISSN 2296-4185
Publisher: Frontiers Media SA
DOI: 10.3389/fbioe.2025.1548539

A comparative analysis of the influence of refractive error on image acuity using three eye models

Author(s): Fabian Debowy, Barbara Pierscionek
Published in: Ophthalmic and Physiological Optics, Issue 44, 2023, Page(s) 182-190, ISSN 0275-5408
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/opo.13251

Statistical Model of Ocular Wavefronts With Accommodation

Author(s): María Mechó-García, María Arcas-Carbonell, Elvira Orduna-Hospital, Ana Sánchez-Cano, Norberto López-Gil, Rute J. Macedo-de-Araújo, Miguel Faria-Ribeiro, Paulo Fernandes, José Manuel González-Méijome, Jos Rozema
Published in: Investigative Ophthalmology & Visual Science, Issue 65, 2024, Page(s) 12, ISSN 1552-5783
Publisher: Association for Research in Vision and Ophthalmology (ARVO)
DOI: 10.1167/iovs.65.12.12

Optical and motor changes associated with lighting and near vision tasks in electronic devices

Author(s): Elvira Orduna-Hospital, Ebrahim Safarian Baloujeh, Rafael Navarro, Ana Sanchez-Cano
Published in: Journal of Eye Movement Research, Issue 16, 2025, ISSN 1995-8692
Publisher: MDPI AG
DOI: 10.16910/jemr.16.2.3

The influence of variations in ocular biometric and optical parameters on differences in refractive error

Author(s): Arezoo Farzanfar, Veronica Lockett‐Ruiz, Rafael Navarro, Carina Koppen, Jos J. Rozema
Published in: Ophthalmic and Physiological Optics, Issue 44, 2024, Page(s) 1000-1009, ISSN 0275-5408
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/opo.13318

Optomechanical assessment of photorefractive corneal cross-linking via optical coherence elastography

Author(s): Matteo Frigelli, Philippe Büchler, Sabine Kling
Published in: Frontiers in Bioengineering and Biotechnology, Issue 11, 2023, ISSN 2296-4185
Publisher: Frontiers Media SA
DOI: 10.3389/fbioe.2023.1272097

Opto-mechanical self-adjustment model of the human eye

Author(s): Mohammadali Shahiri, Agnieszka Jóźwik, Magdalena Asejczyk
Published in: Biomedical Optics Express, Issue 14, 2024, Page(s) 1923, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.484824

Biomechanical simulations of crystalline lens oscillations resulting from the changes in the gaze in an accommodated eye

Author(s): Ali Dahaghin, Milad Salimibani, Agnieszka Boszczyk, Agnieszka Jóźwik, Jorge Grasa, Joanna Przeździecka-Dołyk, Damian Siedlecki
Published in: Frontiers in Bioengineering and Biotechnology, Issue 13, 2025, ISSN 2296-4185
Publisher: Frontiers Media SA
DOI: 10.3389/fbioe.2025.1504769

Dynamic evaluation of corneal cross-linking and osmotic diffusion effects using optical coherence elastography

Author(s): Matteo Frigelli, Philippe Büchler, Sabine Kling
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-67278-1

The Influence of Accommodative Demand on Ocular Aberrations: A Study of Zernike Coefficients Repeatability and Variability

Author(s): María Mechó-García, María Arcas-Carbonell, Elvira Orduna-Hospital, Ana Sánchez-Cano, José Manuel González-Méijome
Published in: Current Eye Research, Issue 49, 2025, Page(s) 1237-1246, ISSN 0271-3683
Publisher: Swets & Zeitlinger
DOI: 10.1080/02713683.2024.2378009

Wavefront Changes during a Sustained Reading Task in Presbyopic Eyes

Author(s): Ebrahim Safarian Baloujeh, José M. González-Méijome
Published in: Sensors, Issue 24, 2024, Page(s) 3866, ISSN 1424-8220
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/s24123866

Changes in Wavefront Error of the Eye for Different Accommodation Targets under the Application of Phenylephrine Hydrochloride

Author(s): María Mechó-García, Iñaki Blanco-Martínez, Paulo Fernandes, Rute J. Macedo-de-Araújo, Miguel Faria-Ribeiro, José Manuel González-Méijome
Published in: Photonics, Issue 10, 2023, Page(s) 381, ISSN 2304-6732
Publisher: MDPI AG
DOI: 10.3390/photonics10040381

Investigation of crystalline lens overshooting: ex vivo experiment and optomechanical simulation results

Author(s): Ali Dahaghin, Milad Salimibani, Agnieszka Boszczyk, Agnieszka Jóźwik, Marta Skrok, Jorge Grasa, Damian Siedlecki
Published in: Frontiers in Bioengineering and Biotechnology, Issue 12, 2024, ISSN 2296-4185
Publisher: Frontiers Media SA
DOI: 10.3389/fbioe.2024.1348774

Modeling biological growth of human keratoconus: On the effect of tissue degradation, location and size

Author(s): Benedetta Fantaci, Begoña Calvo, José Félix Rodríguez
Published in: Computers in Biology and Medicine, Issue 180, 2024, Page(s) 108976, ISSN 0010-4825
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.compbiomed.2024.108976

Retinal reconstruction from peripheral biometry

Author(s): Iñaki Blanco-Martínez, David A. Atchison, Fuensanta A. Vera-Diaz, Jos J. Rozema
Published in: Biomedical Optics Express, Issue 16, 2025, Page(s) 1359, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.549290

The Effect of Accommodation on Peripheral Refraction under Two Illumination Conditions

Author(s): Raquel van Ginkel; María Mechó; Genis Cardona; José M. González-Méijome
Published in: Photonics, 2022, ISSN 2304-6732
Publisher: MPDI
DOI: 10.3390/photonics9050364

Complexity of crystalline lens wobbling investigated by means of combined mechanical and optical simulations

Author(s): Agnieszka Boszczyk, Fabian Dębowy, Agnieszka Jóźwik, Ali Dahaghin, Damian Siedlecki
Published in: Biomedical Optics Express, Issue 14, 2024, Page(s) 2465, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.488176

A detailed methodology to model the Non Contact Tonometry: a Fluid Structure Interaction study.

Author(s): Elena Redaelli; Jorge Grasa; Begoña Calvo; Jose Felix Rodriguez Matas; Giulia Luraghi
Published in: Frontiers in Bioengineering and Biotechnology, 2022, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2022.981665

Localized Refractive Changes Induced by Symmetric and Progressive Asymmetric Intracorneal Ring Segments Assessed with a 3D Finite-Element Model

Author(s): Gonzalo García de Oteyza, Juan Álvarez de Toledo, Rafael I. Barraquer, Sabine Kling
Published in: Bioengineering, Issue 10, 2025, Page(s) 1014, ISSN 2306-5354
Publisher: MDPI
DOI: 10.3390/bioengineering10091014

The Effect of Lens Shape, Zonular Insertion and Finite Element Model on Simulated Shape Change of the Eye Lens

Author(s): Lin Ye, Kehao Wang, Jorge Grasa, Barbara K. Pierscionek
Published in: Annals of Biomedical Engineering, Issue 52, 2024, Page(s) 1982-1990, ISSN 0090-6964
Publisher: Kluwer Academic Publishers
DOI: 10.1007/s10439-024-03491-3

Effect of Small Angle Misalignments on Ocular Wavefront Zernike Coefficients

Author(s): Ebrahim Safarian Baloujeh, Francisco J. Ávila, José M. González-Méijome
Published in: Photonics, Issue 11, 2024, Page(s) 795, ISSN 2304-6732
Publisher: MDPI AG
DOI: 10.3390/photonics11090795

Optical coherence tomography quantifies gradient refractive index and mechanical stiffness gradient across the human lens

Author(s): Sabine Kling, Matteo Frigelli, M. Enes Aydemir, Vahoora Tahsini, Emilio A. Torres-Netto, Leonard Kollros, Farhad Hafezi
Published in: Communications Medicine, Issue 4, 2024, ISSN 2730-664X
Publisher: Nature Publishing Group
DOI: 10.1038/s43856-024-00578-9

Exploring Changes in Ocular Aberrations for Different Fixation and Accommodation Stimuli

Author(s): María Mechó-García, Rute J. Macedo-de-Araújo, Paulo Fernandes, José Manuel González-Méijome
Published in: Photonics, Issue 11, 2024, Page(s) 1090, ISSN 2304-6732
Publisher: MDPI AG
DOI: 10.3390/photonics11111090

Analytical ray transfer matrix for the crystalline lens

Author(s): Rafael Navarro; Veronica Lockett-Ruiz; José L. López
Published in: Biomed Opt Express, 2022, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.466374

Fast and Slow Response of the Accommodation System in Young and Incipient-Presbyope Adults During Sustained Reading Task

Author(s): Ebrahim Safarian Baloujeh, António Queirós, Rafael Navarro, José Manuel González-Méijome
Published in: Journal of Clinical Medicine, Issue 14, 2025, Page(s) 1107, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm14041107

Viscoelastic properties of porcine lenses using optical coherence elastography and inverse finite element analysis

Author(s): Iulen Cabeza-Gil, Vahoura Tahsini, Sabine Kling
Published in: Experimental Eye Research, Issue 233, 2023, Page(s) 109558, ISSN 0014-4835
Publisher: Academic Press
DOI: 10.1016/j.exer.2023.109558

Assessment of Material Properties in Key Components of the Porcine Crystalline Lens During Overshooting

Author(s): Milad Salimibani, Ali Dahaghin, Agnieszka Boszczyk, Jorge Grasa, Damian Siedlecki
Published in: Acta of Bioengineering and Biomechanics, Issue 26, 2025, ISSN 1509-409X
Publisher: Oficyna Wydawnicza
DOI: 10.37190/abb-02463-2024-03

Bi-exponential description for different forms of refractive development

Author(s): Arezoo Farzanfar, Jos J. Rozema
Published in: Journal of Vision, Issue 24, 2024, Page(s) 3, ISSN 1534-7362
Publisher: Association for Research in Vision and Ophthalmology
DOI: 10.1167/jov.24.7.3

Linear fitting of biconic surfaces for corneal modeling

Author(s): Iñaki Blanco-Martínez, José Manuel González-Méijome, Miguel Faria-Ribeiro
Published in: Journal of the Optical Society of America A, Issue 41, 2024, Page(s) 288, ISSN 1084-7529
Publisher: Optical Society of America
DOI: 10.1364/josaa.505248

The potential influence of the ligament of Wieger on the crystalline lens shape

Author(s): Hosna Ghaderi, Sorcha Ní Dhubhghaill, Marie-José Tassignon, Luc Van Os, Carina Koppen, Jos J. Rozema
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-54674-w

Evaluating Retinal Image Quality for Myopia Control Lenses in a Synthetic Accommodative Wavefront Model.

Author(s): María Mechó, Paulo Fernandes, Jose Gonzalez-Meijome, Miguel António Faria Ribeiro
Published in: Biomedical Optics Express, 2025, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/boe.549285

Refractive error maps: A predictive tool for refractive error progression

Author(s): Fabian Debowy, Barbara Pierscionek
Published in: Ophthalmic and Physiological Optics, Issue 45, 2025, Page(s) 577-588, ISSN 0275-5408
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/opo.13444

Improving early detection of keratoconus by Non Contact Tonometry. A computational study and new biomarkers proposal

Author(s): Elena Redaelli, Michael Nana, Begoña Calvo, José Félix Rodríguez Matas, Giulia Luraghi, Jos Rozema, Jorge Grasa
Published in: Journal of the Mechanical Behavior of Biomedical Materials, Issue 152, 2024, Page(s) 106413, ISSN 1751-6161
Publisher: Elsevier BV
DOI: 10.1016/j.jmbbm.2024.106413

Effect of intraocular pressure on crystalline lens oscillations: a computational study using porcine eye model

Author(s): Ali Dahaghin, Milad Salimibani, Agnieszka Boszczyk, Jorge Grasa, Damian Siedlecki
Published in: PLOS ONE, Issue 20, 2025, Page(s) e0320205, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0320205

Pilot study on the dynamic interactions between cardiac activity and corneal biomechanics during eye movements

Author(s): Mohammadali Shahiri, Henryk Kasprzak, Magdalena Asejczyk
Published in: Frontiers in Medicine, Issue 11, 2024, ISSN 2296-858X
Publisher: Frontiers Media SA
DOI: 10.3389/fmed.2024.1484449

Lighting-Induced Changes in Central and Peripheral Retinal Thickness and Shape after Short-Term Reading Tasks in Electronic Devices

Author(s): Elvira Orduna-Hospital; Francisco J. Ávila; Guisela Fernández-Espinosa; Ana Sanchez-Cano
Published in: Photonics, 2022, ISSN 2304-6732
Publisher: MPDI
DOI: 10.3390/photonics9120990