Restoring Odorant detection and recognition in Smell dEficits

Informations projet

Rose

N° de convention de subvention: 964529

DOI

10.3030/964529

Projet clôturé

Date de signature de la CE 24 Août 2021

Date de début 1 Septembre 2021

Date de fin 31 Août 2025

Financé au titre de

• EXCELLENT SCIENCE - Future and Emerging Technologies (FET)

Coût total

€ 2 999 947,50

Contribution de l’UE

€ 2 999 947,50

Coordonné par

CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Documents, reports (8)

Final scientific report on Detection/Discrimination using the iDOM

In this deliverable, we will present the results from the study conducted in Task 6.3 whereby people with olfactory loss will be asked to detect and discriminate odorant molecules using the iDOM.

Technical/scientific review meeting documents M12

These documents are i the draft agendaii presentations to be delivered during the next review meeting

Technical/scientific review meeting documents M30

These documents are : (i) the draft agenda(ii) presentations to be delivered during the next review meeting

Pages on social media/Internal platform/Public website/Logo

This deliverable will consist in the public website and logo of the project as well as initiated social media activities of the Rose project Task 75

Design CMUT sensors

This will be the final deliverable of Task 2.1 aimed at defining the main features required for developed system (i.e. size of the cMUT elements, pixel geometries, electromechanical properties and electromechanical measurements)

Final scientific report on Detection/Discrimination study

Here, we will present the results from the study conducted in Task 6.2 whereby people with olfactory loss will be asked to detect and discriminate odorant molecules using the stimulation device.

Scientific report of SEEG studies

Here, we will present results from the study conducted in Task 5.1 whereby electrical stimulation were applied in various sites of the olfactory system and related areas to set out to examine whether they elicited a smell perception in patients with SEEG.

Set of 10 reference molecules

This deliverable will be the final report of Task 41 consisting whereby we will define a set of 10 reference molecules that can be detected and recognized by the sensors

Demonstrators, pilots, prototypes (1)

DOM gen1: with optical smell sensor

This deliverable will be the second of Task 4.2. Here, wwe will connect the smell sensor with the stimulation array to develop the digital olfaction module (DOM).

Publications

Peer reviewed articles (6)

Hot topic: Mapping of the human intranasal mucosal thermal sensitivity: A clinical study on thermal threshold and trigeminal receptors

Auteurs: Susanne Weise, Pauline Hanslik, Coralie Mignot, Evgenii Glushkov, Arnaud Bertsch, Romain Dubreuil, Moustafa Bensafi, Susanne Fuessel, Thomas Hummel
Publié dans: PLOS ONE, Numéro 19, 2024, Page(s) e0304874, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0304874

A data set of symptoms and needs of individuals affected by COVID-19

Auteurs: Stanley H.B. and Bensafi M.
Publié dans: Scientific Data, 2024, ISSN 2052-4463
Éditeur: Springer Nature
DOI: 10.1038/s41597-024-02961-6

Characterization of a Multi-Channel CMUT Gas Sensor

Auteurs: Charles Boutonnet, Anurupa Shaw, Jean-Claude Bastien, François Blard, Adrien Vialletelle, Vincent Pinon, Christophe Le Blanc, Cyril Herrier, Thierry Livache, Bruno Fain
Publié dans: Journal of Microelectromechanical Systems, Numéro 34, 2025, Page(s) 4-14, ISSN 1057-7157
Éditeur: Institute of Electrical and Electronics Engineers
DOI: 10.1109/jmems.2024.3495539

Olfactory implants: international opinion paper on emerging technologies and clinical applications

Auteurs: K.L. Whitcroft - A.K. Hernandez - P. Andrews - A. Altundag - H. Benkhatar - M. Bensafi - C. Boëx - F. Calegari - D.H. Coelho - R.M. Costanzo - V. Druet - W. Esposito - A. Perez Fornos - S. Gane - C.A. Hintschich - E.H. Holbrook - J. Hsieh - C. Huart - M. Kobayashi - I. Konstantinidis - S.P. Lacour - B.N. Landis - C.S.S. Lipp - A. Macchi - C. Mignot - E. Mori - T. Myuran - H. Nishijima - Z.M. Pate
Publié dans: Rhinology, 2025, ISSN 0300-0729
Éditeur: International Rhinologic Society
DOI: 10.4193/rhin24.523

What do brain oscillations tell about the human sense of smell?

Auteurs: Coralie Mignot, Susanne Weise, Dino Podlesek, Georg Leonhardt, Moustafa Bensafi, Thomas Hummel
Publié dans: Journal of Neuroscience Research, Numéro 102, 2024, ISSN 0360-4012
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/jnr.25335

Identification of the needs of individuals affected by COVID-19

Auteurs: Halina B. Stanley, Veronica Pereda-Campos, Marylou Mantel, Catherine Rouby, Christelle Daudé, Pierre-Emmanuel Aguera, Lesly Fornoni, Thomas Hummel, Susanne Weise, Coralie Mignot, Iordanis Konstantinidis, Konstantinos Garefis, Camille Ferdenzi, Denis Pierron, Moustafa Bensafi
Publié dans: Communications Medicine, Numéro 4, 2024, ISSN 2730-664X
Éditeur: Springer
DOI: 10.1038/s43856-024-00510-1

Conference proceedings (3)

Reverse Engineering and Prototyping of a Nasal Cavity Model for Odorant Detection Experiments

Auteurs: Michele Bertolini, Marco Rossoni, Marina Carulli, Romain Dubreuil, Giorgio Colombo, Monica Bordegoni
Publié dans: Volume 2A: 44th Computers and Information in Engineering Conference (CIE), 2024
Éditeur: American Society of Mechanical Engineers
DOI: 10.1115/detc2024-142171

Stimulation of the Nasal Cavity Using Flexible PCB Electrodes

Auteurs: Clémentine Lipp, Evgenii Glushkov, Halina B. Stanley, Camille Ferdenzi, Maxime Fieux, Arnaud Bertsch, Jürgen Brugger, Moustafa Bensafi
Publié dans: Eurosensors 2023, Numéro 93, 2024, Page(s) 231
Éditeur: MDPI
DOI: 10.3390/proceedings2024097231

Statistical Shape Modelling of the Nasosinusal Anatomy

Auteurs: Michele Bertolini, Silvia Tonghini, Marco Rossoni, Marina Carulli, Susanne Weise, Christian Jan Baldus, Giorgio Colombo, Monica Bordegoni
Publié dans: Volume 1: Acoustics, Vibration, and Phononics; Advanced Design and Information Technologies, 2025
Éditeur: American Society of Mechanical Engineers
DOI: 10.1115/imece2024-144335

Non-peer reviewed articles (2)

[Olfactory and gustatory disorders].

Auteurs: Speth, M. M.; Speth, U. S.; Sedaghat, A. R.; Hummel, T.
Publié dans: HNO, Numéro 4, 2022, ISSN 0017-6192
Éditeur: Springer Verlag
DOI: 10.1007/s00106-021-01132-y

Abstracts zur 96. Jahresversammlung Deutsche Gesellschaft für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie e. V., Frankfurt

Auteurs: S. Weise, H. B. Stanley, C. Lipp, C. Mignot1, K. Garefis, M. Fieux, E. Tsakiropoulou. Genetzaki R. Dubreuil, P. Hanslik, C. Ferdenzi, M. Carulli, A. Bertsch, J. Brugger, T. Hummel, I. Konstantinidis, M. Bensafi
Publié dans: HNO, Numéro 73, 2025, Page(s) 134-324, ISSN 0017-6192
Éditeur: Springer Verlag
DOI: 10.1007/s00106-025-01624-1