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Regeneration of Injured Spinal cord by Electro pUlsed bio-hybrid imPlant

Deliverables

Press release 1

Communication activities released through press at month 12

Fourth interim report

Minutes and reports of the partners meeting 24 months after the start of the project

Modelling of iNSC and MSC cells

Description of 3Dmicrodosimetry of the cells hosted in the scaffolds developed from microscopy images

Press release 2

Communication activities released through press at month 24

Exploitation Plan draft

Draft of the Exploitation Plan for the management of generated knowledge including patenting strategies and possible industrial exploitations

Computational neuronal cells & calcium responses to µPEFs/DC

Neurofunctionalized computational model to predict neuronal response and Ca oscillations induced by PEFs and or DC levels

Dissemination/Communication plan

A strategy to disseminate results will be defined by a plan for resources and actions necessary to prepare corporate dissemination material and communication activities

Kick-off report including risk assessment

ENEA will be in charge of kick off meeting organization with all the beneficiaries to discuss the first actions to do for project starting All the risks related to the project will be also addressed in order to mitigate them

Data Management Plan

Setup of a plan for managing the data generated and collected during the project

Publications

Electric field bridging-effect in electrified microfibrils’ scaffolds

Author(s): Sara Fontana, Laura Caramazza, Paolo Marracino, Irene Cuenca Ortolá, Micol Colella, Noemi Dolciotti, Alessandra Paffi, Fernando Gisbert Roca, Sergiy Ivashchenko, Jorge Más Estellés, Claudia Consales, Marco Balucani, Francesca Apollonio and Micaela Liberti
Published in: frontiers in bioengineering and biotechnology, 2023, ISSN 2296-4185
Publisher: Frontiers
DOI: 10.3389/fbioe.2023.1264406

Electrical Stimulation Increases Axonal Growth from Dorsal Root Ganglia Co-Cultured with Schwann Cells in Highly Aligned PLA-PPy-Au Microfiber Substrates.

Author(s): Fernando Gisbert Roca; Sara Serrano Requena; Manuel Monleón Pradas; Cristina Martínez-Ramos
Published in: International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6362, Issue 3, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23126362

A Strategy for Magnetic and Electric Stimulation to Enhance Proliferation and Differentiation of NPCs Seeded over PLA Electrospun Membranes.

Author(s): Irene Cuenca-Ortolá; Beatriz Martínez-Rojas; Victoria Moreno-Manzano; Marcos García Castelló; Manuel Monleón Pradas; Cristina Martínez-Ramos; Jorge Más Estellés
Published in: Biomedicines; Volume 10; Issue 11; Pages: 2736, Issue 1, 2022, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines10112736

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