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NEutron Capture-enhanced Treatment of neurotoxic Amyloid aggRegates

Project description

DEENESFRITPL

Ionising radiation treatment for Alzheimer's disease

Alzheimer’s disease (AD) is a neurodegenerative condition for which no cure or effective treatments exist. Given the increase in the ageing population, AD cases are expected to rise, posing a significant socioeconomic issue. The EU-funded NECTAR project is proposing an alternative treatment for AD based on ionising radiation. The treatment entails the irradiation of the brain using an external beam of low-energy neutrons which selectively target and destroy the amyloid beta aggregates through specific enhancers capable of crossing the blood–brain barrier. The NECTAR treatment will form the basis for the future application of ionising radiation against other proteinopathies.

Fields of science

Programme(s)

Topic(s)

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-01

Funding Scheme

RIA - Research and Innovation action

Coordinator

UNIVERSITA DEGLI STUDI DI PAVIA
Net EU contribution
€ 255 565,00
Address
Strada Nuova 65
27100 Pavia
Italy

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Region
Nord-Ovest Lombardia Pavia
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,01

Participants (7)

UNIVERSITA DEGLI STUDI DI TORINO
Italy
Net EU contribution
€ 651 305,00
Address
Via Giuseppe Verdi 8
10124 Torino

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Region
Nord-Ovest Piemonte Torino
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI
Italy
Net EU contribution
€ 665 500,00
Address
Via Mario Negri 2
20156 Milano

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Region
Nord-Ovest Lombardia Milano
Activity type
Research Organisations
Non-EU contribution
€ 0,00
RAYLAB SRL
Italy
Net EU contribution
€ 606 000,00
Address
Via Monte Di Pieta 2
24043 Caravaggio

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Nord-Ovest Lombardia Bergamo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
INSTITUT DE RADIOPROTECTION ET DE SURETE NUCLEAIRE
France
Net EU contribution
€ 233 107,50
Address
Av De La Division Leclerc 31
92260 Fontenay Aux Roses

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Region
Ile-de-France Ile-de-France Hauts-de-Seine
Activity type
Research Organisations
Non-EU contribution
€ 0,00
STOCKHOLMS UNIVERSITET
Sweden
Net EU contribution
€ 656 585,00
Address
Universitetsvagen 10
10691 Stockholm

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Region
Östra Sverige Stockholm Stockholms län
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITAETSKLINIKUM ESSEN
Germany
Net EU contribution
€ 39 500,00
Address
Hufelandstrasse 55
45147 Essen

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Region
Nordrhein-Westfalen Düsseldorf Essen, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 79 716,25
UNIVERSITATSKLINIKUM JENA
Germany
Net EU contribution
€ 30 000,00
Address
Kastanienstr.1
07747 Jena

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Region
Thüringen Thüringen Jena, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

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EC signature date: 20 January 2021
Last update: 15 June 2022
Record number: 233332

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Permalink: https://cordis.europa.eu/project/id/964934

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