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APPLICATION OF EPITOPE LIBRARIES TO THE DEVELOPMENT OF RAPID METHODS OF DISEASE DIAGNOSIS IN THE HORSE

Objective



The objective is to improve disease control throughout the EU by developing better diagnostic techniques for equine infectious diseases.
Specific objectives are:
- Establish a Community Standard by novel application of recently described molecular technology (phage epitope libraries) to design and implement rapid pathogen-specific diagnostics for equine diseases.
- Use post-infection and post-vaccination horse sera to select phage bearing important peptide antigens for diagnostic tests (a novel approach).
- Develop phage library to detect and discriminate between vaccination and infection induced serum antibodies in horses.
- Apply diagnostic tests to discriminate between vaccination and infection with EHV-1 (abortigenic and parlytic type of equine herpesvirus) and EHV-4 (respiratory disease virus).
- Apply diagnostic tests to discriminate between vaccination and infection with equine influenza virus (ETV).
- Apply diagnostic tests to discriminate between vaccination and infecction withequine arteritis virus (EAV, causes respiratory disease, abortion, paralysis and establishes latent infections in stallions causing venereal spread of infection to breeding mares).

Call for proposal

Data not available

Coordinator

Animal Health Trust
Address

CB8 7DW Newmarket
United Kingdom
 

Participants (3)

Aristotelian University of Thessaloniki
Greece
Address
University Campus
54006 Thessaloniki
 
Centre National d'Études Vétérinaires et Alimentaires (CNEVA)
France
Address
22 Rue Pierre Curie
94701 Maisons-alfort
 
Istituto Zooprofilattico Sperimentale di Venezia
Italy
Address
Via G. Orus 2
35129 Padova