Objective
- To describe better the molecular defects leading to familial Mediterranean fever (FMF).
Expected Outcome
- The molecular basis of FMF and other forms of arthritis should be understood better, thus providing an opportunity for improved early diagnosis, therapy and prevention.
- Identification of a sufficient number of FMF families and preparation of a detailed clinical description of a series of Turkish, Spanish and non-Askhenazi Jewish patients with FMF serving as a basis for an optimal genetic mapping of the molecular defects in FMF;
- Genetic and physical mapping of the candidate regions of the FMF gene, first through the exclusion of gene-regions that have a recombinant event in an affected individual, and second, by a continuous mapping of identified candidate regions. The location of the disease gene will then be identified by molecular genetic techniques and through studying linkage disequilibria in each of the ethnic groups.
Fields of science (EuroSciVoc)
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Programme(s)
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Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
07001 Palma de Mallorca
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.