CORDIS provides links to public deliverables and publications of HORIZON projects.
Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .
Exploitable results
Modification of the genomes of parvoviruses H-1 and MVM, attempting to make them suitable linear vectors, has resulted in:
production of recombinant parvoviruses showing transduction specificity for oncogene-transformed cells and having potential for cancer gene therapy;
programmed cell killing by means of inducible clones of parvoviral genes encoding nonstructural proteins;
demonstration and unravelling of the oncolytic activity of parvoviruses, raising prospects of anticancer applications.
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