Objective
PROJECT 1:
NON-STOCHASTIC EFFECTS: THIS PART OF THE PROGRAMME AIMS TO ANSWER THE FOLLOWING IMPORTANT PRACTICAL RADIATION PROTECTION QUESTIONS:
1. IS THERE A MINIMUM AREA THAT NEEDS TO BE IRRADIATED TO INDUCE SUCH EFFECTS AS MOIST DESQUAMATION (EPIDERMAL DAMAGE) OR ULCERATION (DERMAL DAMAGE).
2. WHAT ARE THE THRESHOLD DOSES FOR DESQUAMATION AND ULCERATION AND HOW DO THEY VARY AS A FUNCTION OF AREA IRRADIATED.
3. HOW DO THE THRESHOLD DOSES FOR GIVEN AREAS VARY WITH THE ENERGY (PENETRATION) OF THE ALPHA AND BETA PARTICLES.
4. WHAT ARE THE RBE VALUES FOR ALPHA PARTICLES FOR THESE NON-STOCHASTIC ENDPOINTS.
5. HOW DO THE RESPONSE CURVES FOR DESQUAMATION AND ULCERATION VARY WITH THE PROTRACTION OF ALPHA AND BETA DOSES.
PROJECT 2:
STOCHASTIC (CARCINOGENESIS) STUDIES: IN PARALLEL WITH THE NON-STOCHASTIC EXPERIMENTS, STUDIES OF SKIN CANCER INDUCTION ARE PROPOSED. THESE WILL COMPARE PREDICTED DOSE RESPONSE CURVES WITH THE OBSERVED TUMOUR INCIDENCE IN MICE GIVEN UNIFORM AND NON-UNIFORM BETA IRRADIATION.
The most important message, of this long term study of nonuniform beta radiation exposure of mouse skin, is that the results are in direct contradiction to the hot particle hypothesis and indicate that nonuniform exposure produces far fewer tumours than uniform exposure. This should be reasuring to those in radiation protection who are currently concerned about the biological effectiveness of such particulates.
1. NON-STOCHASTIC EFFECTS OF ALPHA AND BETA RADIATION ON MOUSE SKIN.
2. STOCHASTIC EFFECTS OF ALPHA AND BETA RADIATION ON MOUSE SKIN.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Data not available
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
EC1A 7BE London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.