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Content archived on 2024-04-15

LIMITATION OF PATIENT EXPOSURE TO RADIATION FROM EMERGING MEDICAL DIAGNOSTIC PROCEDURES IN HIGH MORBILITY DISEASE AREAS

Objective

ESTABLISHMENT OF PROTOCOLS FOR DISEASE SPECIFIC DIAGNOSIS AND EXPOSURE REDUCTION; SPECIFICITY AND SENSITIVITY OF VARIOUS DIAGNOSTIC METHODS.
Comparisons have been made of nuclear cardiology versus 2-dimensional echocardiography for the detection, quantitation and follow up study of myocardial disease.
The diagnostic efficacy of immunoscintigraphy with radioactive monoclonal antibodies has been compared to that of bidimensional echography.

The role of functional indices, derived from radionuclide angiography (RNA), to diagnose early myocardial disease in patients with ventricular arrhythmias and/or left bundle branch block (LBBB), but without clinical evidence of heart failure or other cardiac and systemic diseases, has been assessed in comparison with radiological invasive, and nonradiological noninvasive procedures. The presence of organ specific cardiac autoantibodies was checked, in view of developments in the field of radioimmunoscintigraphy of myocardial disease.
DEVELOPMENT AND TESTING OF ADEQUATELY ASSESSED, RELIABLE AND AGREED PROTOCOLS DEFINING THE ACTUAL DIAGNOSTIC EFFICACY OF:
1. NUCLEAR CARDIOLOGY PROCEDURES (VERSUS BIDIMENSIONAL ECHOCARDIOGRAPHY).
2. IMMUNOSCINTIGRAPHY WITH RADIOACTIVE MONOCLONAL ANTIBODIES (VERSUS BIDIMENSIONAL ECHOGRAPHY).

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Coordinator

Università degli Studi di Pisa
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Lungarno Pacinotti 45
56100 Pisa
Italy

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