Objective
Nineteen infant and thirteen pregnant chimpanzees have been tested. The first experiments revealed that the uptake of radioiodine by the thyroid in two one year old chimpanzees was already very low without the administration of stable iodide. Subsequent determination of the urinary iodide levels showed that the daily output of the chimpanzees was 40 times normal, indicating the presence of an unknown source of iodide exposure. This source proved to be an iodide containing detergent used for disinfecting the housing of the chimpanzees. The thyroidal uptake of radioiodine in the two infant chimpanzees was 2.3% and 1.3% in this situation (October 1988). As expected, these values could hardly be reduced by adding extra iodide. After these findings the iodide containing agent was replaced and the excretion of iodide reached normal values. Four months later the thyroidal uptake of iodine 123 had increased in both animals, to 11.7% and 10%. Upon the administration of a dose of 0.5 mg potassium iodide /kg/day thyroidal uptake was effectively blocked. There was no identification of severe thyroid disorders, however, in either of the 2 animals.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences inorganic chemistry alkali metals
- natural sciences chemical sciences inorganic chemistry halogens
You need to log in or register to use this function
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Data not available
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Data not available
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
2280 HV RIJSWIJK
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.