Drosophila European Stock Centres

Informations projet

N° de convention de subvention: BIO4950202

Projet clôturé

Date de début 1 Janvier 1996

Date de fin 31 Decembre 1999

Financé au titre de

• Specific research, technological development and demonstration programme in the field of biotechnology, 1994-1998

Coût total

Aucune donnée

Contribution de l’UE

Aucune donnée

Coordonné par

UNIVERSITY OF UMEAA
Sweden

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Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Résultats exploitables

Curation, characterisation, distribution and information display of mutant Drosophila stocks

The contents of the European Drosophila Stock Centres in Umeå, Sweden, and Szeged, Hungary have been expanded to over 10,000 well documented mutant Drosophila stocks. Most of the stocks have been donated by European Drosophila research labs, or been produced at the partner labs, partly also within this project. The collection in Umeå mainly consists of stocks with visible mutations, chromsomal aberrations, and genetical tools for research purposes. The Szeged Stock Centre is more directed towards maintaining collections of P-element induced lethal mutant stocks. These lines have during this project been made available to the European research community and is an invaluable source of mutants that has been screened for a large variety of purposes. In parallel, the characterization of these stocks have continued. All strains are freely available to researchers in the Member states. Stock requests from the two Stock Centres has increased every year since the start of this project. In 1997, Umeå shipped 3,684 stocks to labs around the world. During 1999, Umeå and Szeged together shipped over 22,000 lines. One cause to this increase was that the genetic information of all mutant strains at both Stock Centres was displayed in the database « FlyBase » on Internet and thus was made easily available to the European research community. Fly requests also became extremely simplified, when a fly order form was included in FlyBase, which was connected to the stock lists and which sent the requests electronically to the two European Stock Centres. The partnership labs have played a vital role in the characterization of the P-element lines and in actively exploiting the P-element line collection within their field of expertise, exemplified by neurogenesis, tumour suppression, cell cycle regulation, cell differentiation, cell signalling, gene regulation and chromatin structure.