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Contenu archivé le 2024-04-30

The industrial use of genome resources in Europe

Objectif



This multi-centred research project (GB, FR, BE) aims to assess the impact of EU basic research programmes in genome analysis (Arabidopsis, Yeast, Drosophila, B. subtilus, various extremophiles and human) which now appear to have clear industrial applications. The overall goal is to provide an analysis by which the industrial utility of genome information can be evaluated and the mechanisms for optimal European exploitation identified. Europe has played a major role in the application of sequencing and mapping technologies in collaborative genetic research which is leading to the definitive description of the complete genetic (DNA) material in whole organisms, from pathogens to humans. Determining how industry can best exploit European strength in genome analysis through collaboration and technology transfer between the public and private sector will be a central objective of the research.
Although industrial strategies towards the commercial development of genome data are at an early stage, there is no doubt that research in this area is being actively pursued by large and small companies in Europe, the US and Japan. Despite the major European commitment to public sector genomics, there are no European companies in this area. As the commercial exploitation of genome research gathers pace world-wide, it is clearly vital to understand how European companies are responding. An essential step in this direction is an analysis aiming to reveal which European MNEs and SMEs use genome information and for what purpose.
In order to achieve the objectives, the research has been divided into four discrete but related work packages. These are: (a) a comprehensive analysis of the sectoral specialization of European companies using genome information, from SMEs to multinationals (MNEs); (b) an evaluation of the commercial utility of genome information to public domain SMEs and European MNEs; (c) an analysis of the nature and significance of research collaboration in DNA sequencing and mapping between the public and private sectors and within the private sector; (d) an appraisal of the relative importance of European in-house private sector genome projects as compared to those financed by the public sector. Emphasis throughout the proposed research will be given to the following programmes: yeast, Arabidopsis, Bacillus subtilus and human.
This project is of major importance to the EU. Mechanisms to promote European competitiveness in biotechnology where EU programmes have already made substantial investment, are urgently required. The research proposed here is particularly timely because industrial participation is set to expand as genome projects nearing completion are moved onto the next stage of functional analysis.

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UNIVERSITY OF SUSSEX
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