Development of nematode resistant crops by gene transfer of a broad spectrum nematode resistance system

Project Information

Grant agreement ID: BIO4969033

Project closed

Start date 8 November 1996

End date 31 March 1997

Funded under

• Specific research, technological development and demonstration programme in the field of biotechnology, 1994-1998

Total cost € 0,00

EU contribution No data

Coordinated by

Norika - Northring - Potato Breeding Company GmbH
Germany

Objective

Yield losses due to nematode infestation of crops are a problem throughout the EU. Natural resistance traits in crops usually confer resistance only to a subset of pathotypes but this resistance can be broken by selection of new more virulent pathotypes. This problem could be solved by a broad spectrum nematode resistance developed by MOGEN. This resistance system proved to be effective in a model plant. The aim of the project is to use this resistance system in cultivars of potato and other crops. The resistance system should firstly be developed in potato and will require modifications to achieve an optimal effect in other crops. Furthermore, suitable commercial cultivars need to be selected for cell culture and gene transfer experiments. Following transformation experiments, stable transformants have to be selected and screened for their nematode resistance. The comparison of two cultivars of different crops transformed by the resistance system will help to assess the effectiveness of the system used and reveal possible side effects on the plant or tubers/seeds. Yield losses due to nematode infestation of crops are a problem throughout the EU. Natural resistance traits in crops usually confer resistance only to a subset of pathotypes but this resistance can be broken by selection of new more virulent pathotypes. This problem could be solved by a broad spectrum nematode resistance developed by MOGEN. This resistance system proved to be effective in a model plant. The aim of the project is to use this resistance system in cultivars of potato and other crops. The resistance system should firstly be developed in potato and will require modifications to achieve an optimal effect in other crops. Furthermore, suitable commercial cultivars need to be selected for cell culture and gene transfer experiments. Following transformation experiments, stable transformants have to be selected and screened for their nematode resistance. The comparison of two cultivars of different crops transformed by the resistance system will help to assess the effectiveness of the system used and reveal possible side effects on the plant or tubers/seeds.

Fields of science

• medical and health sciences › medical biotechnology › genetic engineering › gene therapy
• agricultural sciences › agriculture, forestry, and fisheries › agriculture › horticulture › vegetable growing › root crops

Programme(s)

• FP4-BIOTECH 2 - Specific research, technological development and demonstration programme in the field of biotechnology, 1994-1998

Topic(s)

• 03 - Plant and animal biotechnology

Call for proposal

Data not available

Funding Scheme

EAW - Exploratory awards

Coordinator

Norika - Northring - Potato Breeding Company GmbH

• EU contribution: No data
• Address: 4,Parkweg ; 18190 Groß Lüsewitz ; Germany
• Total cost: No data

Participants (1)

Mogen International NV trading as ZENECA MOGEN

Netherlands

• EU contribution: No data
• Address: 97,Einsteinweg ; 2333 CB Leiden
• Total cost: No data