Objective
The principle objectives of this proposal concern the development of simple, inexpensive techniques to measure the level of cytokines and other functional proteins, and their specific mRNA, within defined cell populations using multi-parametric flow cytometry. The aim is to develop these tests into simple assays of clinical relevance. Research is required to develop and characterise the required fluorochrome conjugated anti-cytokine monoclonal antibodies and particularly to develop specific fluorchrome conjugated oligonucleotide probes to detect cytokine mRNA. It is also necessary to investigate and develop techniques for the culture and labelling of cells simultaneously with these reagents, to permit the concurrent flow cytometric detection of both protein and mRNA within individual cells. These assays have the potential to revolutionize the investigation of a wide range of diseases, both at diagnosis and during treatment.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
OX5 1JE Oxford - Oxfordshire
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.