Objective
Cyclodextrins are cyclic oligosaccharides consisting of alpha (1,4)-linked D-glucopyranosyl units.
As organic materials they haveimportant advantages: a hydrophobic cavity which can encapsulate molecules such as drugs; relative ease of selective chemical modification compared with other oligosaccharides; availability on an industrial scale. In work by the UCD group, arange of novel amphiphilic and dendrimeric cyclodextrins have been synthesised which form both lyotropic and thermotropic liquid crystals. These cyclodextrins are therefore the first molecules to show the full range of mesogennic properties. The most interesting possibility raised by self assembling host molecules, is that of bridging two chemistries, host-guest and supra molecular, by formation of host-guest complexes within the molecular assemblies.
In addition to these fundamental possibilities, the supramolecular arrays of host-guest molecules have important implications for drug delivery, chiral separations and chiral synthesis. The laboratory's main interest is in the first of these and in the development of host molecular assemblies such as liposomes, which would act as carriers and vectors for the larger and more labile drugs such as peptides and oligonucleotides.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biochemistry biomolecules
- engineering and technology materials engineering liquid crystals
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
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Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
7500 AE Enschede
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.