Objective
In this proposal, four laboratories from the Eastern European countries intend to join the EC Concerted Action for the coordination of Cystic Fibrosis research and therapy (PL 921391). This project has the following objectives:
*to develop patient data bases to record infornmation correlating genotype with clinical severity of the disease,
*to develop testing methods, by searching for common mutations, or by scanning for new mutations. This will allow to characterize the spectrum of CF defects in each country and to provide the data obtained in the existing European data base of CF mutations,
*to develop central reference laboratories with appropriate training of laboratory personnel,
*to implement effective population screening programmes (carrier screening and neonatal screening).
Some objectives are more specific to certain centres.
*The Estonian team focuses its efforts on developing a new and attractive method for mutation detection, based on fluorescent prinner extension analysis.
*One of the main objectives pursued by the centre from the Czech Redublic is focused on the study of infectious factors of Pseudomonas aeruginosa in CF patients (exogeneous factors, phenotypic and genotypic characters of the strains), as well as the development of an animal model for chronic infection and the development of immunomodulators which could be used in therapy.
Finally,this proposal will establish a high level of skill in the various participating laboratories. A network of information and support will be set up to strengthen CF research in these countries.
Fields of science (EuroSciVoc)
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
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Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
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Funding Scheme
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Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
94010 Créteil
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.