Objectif The Chromosome 21 con sortium would like to increase the number of ressources available for mapping this chromosome and support the proposal of two groups from Russia: P 13 and P 14. The proposal of P 14 is to fill the gaps existing around the centromere and in the telometric region in the first generation map produced by P 5 in the preceding consortium (92-93) and by the CEPH-Genethon group: P 14 proposed to localize and characterize existing cosmid clones and produce new clones. Sequencing of these cosmids will also bring informations on the role of consensus centromeric or telemeric sequences. The proposal of P 13 is to participate to the construction of the transcriptional map: P13 has constructed a library of chromosome 21 heterogeneous nuclear c DNA (h nc DNA) and proposes to include this library in the list of libraries available to the consortium members. P 13 intends to produce new ETSs, to map mew genes and to isolate regulatory sequences located in gene introns. P 13 and P 14 would bring new ressources to the chromosome 21 consortium and would participate to the construction of an integrated genetic, physical and transcriptional map of chromosome 21. Programme(s) IC-PECO/COPERNICUS - Scientific and technological cooperation between the European Community and European non-member countries, 1992- Thème(s) 0202 - CEEC participation in BIOMEDICAL AND HEALTH RESEARCH programme (HUMAN GENOME) Appel à propositions Data not available Régime de financement CSC - Cost-sharing contracts Coordinateur Centre National de la Recherche Scientifique Contribution de l’UE Aucune donnée Adresse Rue de Sèvres 75743 Paris France Voir sur la carte Coût total Aucune donnée Participants (2) Trier par ordre alphabétique Trier par contribution de l’UE Tout développer Tout réduire NATIONAL RESEARCH CENTER OF MENTAL HEALTH - RUSSIAN ACADEMY OF MEDICAL SCIENCES Russie Contribution de l’UE Aucune donnée Adresse 2,Zagorodnoe Sh 2 113152 MOSCOW Voir sur la carte Coût total Aucune donnée Shemyakin Institute of Bioorganic Chemistry Russie Contribution de l’UE Aucune donnée Adresse 16/10,Miklukcho - Maklaya street 117871 Moskva Voir sur la carte Coût total Aucune donnée
