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DNA vaccination of aquaculture fish with emphasis on VHSV in rainbow trout as a model

Objective

The proposed project concerns the development of DNA vaccines for application in farmed fish using VHS virus infection in rainbow trout as a model. Focus will be the development of vaccine formulations that provide high efficacy by the different routes of administration currently used in aquaculture. Assessment of vaccine safety is also included.

1. preparation and testing of DNA vaccine constructs
2. to identify and develop an optimal formulation for delivery of a DNA vaccine by injection and immersion in rainbow trout using VHS as a model
3. to perform a limited characterisation of the humoral and cellular immune response following DNA vaccination against VHS compile data
4. to present a summary safety report in co-operation with project FAIR PL98-4003 and 4026.

Funding Scheme

CSC - Cost-sharing contracts

Coordinator

ALPHARMA
Address
Harbitzalleen 3
0212 Oslo
Norway

Participants (4)

DANISH VETERINARY LABORATORY
Denmark
Address
2,Hangoevej 2
8200 N Aarhus C
Istituto Zooprofilattico Sperimentale delle Venezie
Italy
Address
Via Romea 14/A
35020 Legnaro (Pd)
University of Aberdeen
United Kingdom
Address
2 Tillydrone Avenue
AB9 2TN Aberdeen
University of Oslo
Norway
Address

0316 Oslo