The proposed project concerns the development of DNA vaccines for application in farmed fish using VHS virus infection in rainbow trout as a model. Focus will be the development of vaccine formulations that provide high efficacy by the different routes of administration currently used in aquaculture. Assessment of vaccine safety is also included.
1. preparation and testing of DNA vaccine constructs
2. to identify and develop an optimal formulation for delivery of a DNA vaccine by injection and immersion in rainbow trout using VHS as a model
3. to perform a limited characterisation of the humoral and cellular immune response following DNA vaccination against VHS compile data
4. to present a summary safety report in co-operation with project FAIR PL98-4003 and 4026.
Funding SchemeCSC - Cost-sharing contracts
8200 N Aarhus C
35020 Legnaro (Pd)
AB9 2TN Aberdeen