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Content archived on 2024-05-15

Gene radiation interaction: their influence on pre-menopausal breast cancer risk after chernobyl

Objective

The overall objective of this proposal is to examine the aetiology of pre-menopausal breast cancer after the Chernobyl accident. Specific objectives are to evaluate the role of radiation and genetic modifiers in increases in breast cancer incidence in Belarus and Ukraine and to study the possible interaction between radiation exposure and genetic alterations in genes (BRCA1, BRCA2, ATM) known to influence radiation sensitivity and the risk of breast cancer development.

The proposed project consists of 5 closely interrelated workpackages:
1 - Descriptive epidemiology of breast cancer in contaminated areas of Belarus and Ukraine;
2 - Establishment and testing of mechanisms and procedures for the proposed case-control study;
3 - Phased implementation of the case-control study;
4 - Molecular analysis of BRCA1, BRCA2 and ATM;
5 - Development and testing of dose reconstruction method.

Fields of science (EuroSciVoc)

CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.

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Programme(s)

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Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

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Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

CSC - Cost-sharing contracts

Coordinator

INTERNATIONAL AGENCY FOR RESEARCH ON CANCER
EU contribution
No data
Address
150,Cours Albert-Thomas 150
69372 LYON
France

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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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Participants (3)

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