Risk of thyroid cancer following exposure to I-131 early in life

Objective

This proposal if for bringing together formally data from a number of recently and soon to be completed epidemiological studies of thyroid cancer in relation toI-131 exposure in childhood and adolescence. The studies have been carried out in Belarus, Russia, French Polynesia, the US (Hanford site) and the Marshall Islands, in populations with different genetic backgrounds and distributions of host and environmental risk factors.

This proposal would allow:
1) a more precise evaluation of the risk of thyroid cancer related to exposure to I-131 in childhood and adolescence and;
2) comparing estimates of thyroid cancer risk in relation to exposure to iodine isotopes across studies in different settings and;
3) a study of the role of environmental and host factors that may modify radiation induced thyroid cancer risk. As such, it would maximise the information that can be drawn to evaluate the risk of thyroid cancer related to exposure to I-131 in childhood and adolescence and to evaluate the role of environmental and host factors that may modify radiation induced thyroid cancer risk.

Programme(s)

• FP5-EAECTP C - Research and training programme (Euratom) in the field of nuclear energy (1998 to 2002)

Topic(s)

• 2.1.3.-1.1. - Risk estimates for exposures at low dose and low dose rate

Funding Scheme

CON - Coordination of research actions

Coordinator

INTERNATIONAL AGENCY FOR RESEARCH ON CANCER

Address

150,Cours Albert-thomas 150
69372 Lyon
France

Participants (6)

BELARUSSIAN CENTER FOR MEDICAL TECHNOLOGIES, COMPUTER SYSTEMS, ADMINISTRATION AND MANAGEMENT OF HEALTH

Belarus

Address

P. Brovki Str.
220600 Minsk

GRAY LABORATORY CANCER RESEARCH TRUST

United Kingdom

Address

Mount Vernon Hospital
HA6 2JR Northwood

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

France

Address

Rue Camille Desmoulins 39, Institut Gustave Roussy
94805 Villejuif

KAROLINSKA INSTITUTE

Sweden

Address

Doktorsringen 5
171 71 Stockholm

MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH

Italy

Address

Via Eritrea 62
20157 Milano

MEDICAL RADIOLOGICAL RESEARCH CENTRE - RUSSIAN ACADEMY OF SCIENCES

Russia

Address

4,Koroleva Street 4
249020 Obninsk