Objetivo Msenod40 is expressed in differentiating cells from the nodule primordi and in spontaneous nodules of Medicago plants It is proposed that this genes might act as "riboregulators", a recently described class of untranslated RNAs involved in differentiation, and we are now analysing their role on nodule morphogenesis and other differentiation processes. We propose to construct transgenic plants that overexpress the enod40 gene in sense and antisense orientation using constitutive, inducible and/or tissue specific promoters, to analyze its role "in planta". In parallel, using rapid bioassays, structure-function studies will be performed on the Mtenod40 RNA to delimit biologically active regions involved in cell proliferation. This will allow to conclusively answer if any of the small ORFs can indeed be transated or if a novel function the RNA in the cell may be stablished in relation with plant differentiation. Ámbito científico natural sciencesbiological sciencesgeneticsRNA Programa(s) FP4-TMR - Specific research and technological development programme in the field of the training and mobility of researchers, 1994-1998 Tema(s) 0302 - Post-doctoral research training grants TL12 - Plant Sciences Convocatoria de propuestas Data not available Régimen de financiación RGI - Research grants (individual fellowships) Coordinador CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE Aportación de la UE Sin datos Dirección Avenue de la Terrasse 1Bètiment 23 91190 GIF SUR YVETTE Francia Ver en el mapa Coste total Sin datos Participantes (1) Ordenar alfabéticamente Ordenar por aportación de la UE Ampliar todo Contraer todo Not available España Aportación de la UE Sin datos Dirección Ver en el mapa Coste total Sin datos